DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7c and nmr-2

DIOPT Version :9

Sequence 1:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001256640.1	Gene:	nmr-2 / 180002	WormBaseID:	WBGene00003775	Length:	990	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	90/473 - (19%)
Similarity:	167/473 - (35%)	Gaps:	110/473 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 VATFEHRPYVIIED-DP---KTPGGR-------SIHGIEGL------------------IFRSLA 253
            |.|....|::.:.| ||   |.||.:       .:...:|.                  :...||
Worm   465 VVTLHEPPFIAVSDVDPDTQKCPGNQGSICDWGDVEYTDGAGVKKNRTLLKCCSGYCVDLLNKLA 529

  Fly   254 ERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARS---DLMLPSTSYT 315
            ..:.||..|.:.:|:..| :..:..:.|::..::..:.::.......:..|:   |..||... |
Worm   530 NDIGFTYTLYKVRDEKWG-LKTENGWNGLIADLMHNKADMCVTSLKLNSERARDIDFSLPFLD-T 592

  Fly   316 SFPIVLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITAL-------------- 366
            ...|::.:.| |.:||...| .||.|..|..||      ||.|.:..|:..
Worm   593 GISIIVKIRS-GVLSPTAFL-EPFEYSTWVIIL------FVCIHVAAISIFLFEWVSPYSFNMQK 649

  Fly   367 --PGLRNLVLGRRNRLPFMGMWASLL-GGLALYNPQRNFARYILVMWLLQTLILRAAYTGQLYLL 428
              |......|.|...|    :||:|. ..::...|:...:|.:.::|....|...|.||..|...
Worm   650 YPPPEHKFSLFRSYWL----VWATLFSASVSTDVPKSTVSRLMALVWAAFGLTFLAVYTANLAAF 710

  Fly   429 L------QDVE-MRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAV-----------LS 475
            :      .|:. :..|:.:........:.|..:....|  .::| ..|:|.:           ::
Worm   711 MITRVQYYDLSGIHDPMLNFPHDQKPPFRFGTVDGGNT--HETM-KRNWHKMHEYVKHNKYFRMN 772

  Fly   476 LEESLYRLRDED-DPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPLMT----APLTFY------ 529
            :...:..:::|: |..|..|::      .|:.:|.:..      ..|||    |.:|.|
Worm   773 ISAGIEAVKNEELDAFIYDAVV------LDYWAGKDAN------CALMTVGKWASMTGYGIGFPK 825

  Fly   530 MRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLY 594
            ..||:..   ::..::.....|.:.|.:..::............:..||.|......||..||..
Worm   826 NSPHTSL---VNHYMLQYQQKGDLERLQNFWLTGACTPDSHSQTQSAPLGIENFLSAFVLLAGGI 887

  Fly   595 LVALIVFILEILTTNHRR 612
            :|::||...|.:...|.|
Worm   888 IVSVIVLGFEHIYCMHLR 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/90 (18%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	51/295 (17%)
nmr-2	NP_001256640.1	rSAM_ocin_1	<54..>108	CDD:274893
		Periplasmic_Binding_Protein_type1	102..443	CDD:385651
		Periplasmic_Binding_Protein_Type_2	460..860	CDD:389745	77/426 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910