Protein Alignment Ir7c and glr-5

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_505244.1
• Gene: glr-5 / 179251
• WormBaseID: WBGene00001616
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 702
• Identity: 133/702 - (18%)
• Similarity: 229/702 - (32%)
• Gaps: 237/702 - (33%)

  Fly     8 NVSLVYALVWAIDNYYGMAT-----STPLAVVQFP------TSRESRR-----------LHNDLI 50
            |:.::.| |:..|..|..|.     |:.:.:...|      :||.||:           :||||
 Worm   307 NLKMMEA-VFTFDAVYAFANVFNELSSHMQMNDVPQTLCRKSSRNSRKYQHGRSLIDNIVHNDL- 369

  Fly    51 DAALGRSSGTGRIQFLLEDDRVEMTETDTDPPPPSGLTGRPIAIWFLDSLRSYFRLEMYLNQLGS 115
               .|.|....|                        |.|.|        |:|.|.:.:.|  ||
 Worm   370 ---HGLSGDLRR------------------------LNGHP--------LKSNFSMRIQL--LG- 396

  Fly   116 PYKRNGFFLVIYTG-LED----QPMESLKIMFRRLLNMYVLNVNVFLQRDGTVHLYTYYPYGPHH 175
                       |:| |:|    :|               ..||:|.:..|....|
 Worm   397 -----------YSGRLDDIGFWEP---------------ATNVHVNMSGDSKAQL---------- 425

  Fly   176 CQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRS 240
             |.::.|    ..:|          ||.|.            |.|...||||:::.:.......|
 Worm   426 -QRNVQV----SDEL----------KPHFR------------VTTIMERPYVMLKKNHYELDANS 463

  Fly   241 IHGIEGLIFRSLAE---RMNFTIKLVEQKDKNRG-EILPDGNFTGILKMMVDGEVNLTFVCFMYS 301
              ..||.....|||   .:.||..:...||...| :...:|::.|::..::.||..:.......:
 Worm   464 --KFEGFCIDLLAELSKDLGFTYTIHAVKDGKYGNDKYGNGSWDGMMGEILRGEAEMAVAPLTVN 526

  Fly   302 KARSDLMLPSTSYTSFPIVLVVPSGGSISP-MGRLTRPFRYIIWSCILVSLI---FGFVLICLLK 362
            ..||:.:..:..:.|..|.::........| :.....|..:.||:.|..|:|   .|...:.  .
 Worm   527 YRRSEAVDFTKPFLSLGISILYKVPDDQQPDLFSFLNPLSWQIWTAIATSIITVTLGMYFVA--N 589

  Fly   363 IT--------------------ALPGLRNLVLGRRNRLPFMG-MW---ASLLGGLALYNPQRNFA 403
            :|                    |....:...:...|...|.. :|   :::|.|...:.|:....
 Worm   590 VTPYEWNLNFSCCTAHEPHPAAAFATNQEAPIVMSNNYSFWNTVWYVLSTMLKGGCDFGPRAVST 654

  Fly   404 RYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKD----------------YEFR 452
            |.:...|.:..|::.:|||..|..:|.......|||:|.::..:.                .|.|
 Worm   655 RLLGGTWWVFYLVIISAYTANLAAVLTVSRPYIPIKNLDDLANQTTISYGTIRGGSTMQFFQESR 719

  Fly   453 ILPALR----TIFKDSMPTTNFHAV---LSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPN 510
            |...::    ...||...|:|...|   ||:..:.              |::.|..:::.:...|
 Worm   720 IAAHVKMWQYMKDKDVFVTSNGKGVERALSMNYAY--------------LMESTSLEYETQQNCN 770

  Fly   511 KRHLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYM-------------- 561
               ||.:...|.:......:...|.:..||.|.|:.....||:...:..:.
 Worm   771 ---LTQIGGVLGSKGYGIALAKKSEWTDRISRQILLYAKRGIIEMKKTKWWRSKGAACASTASAV 832

  Fly   562 --DRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEILTTNHR 611
              ||.            .||::.::|:|:......::|.||.|.|::   ||
 Worm   833 KHDRF------------ALSMYNVAGLFITLGVGIVLAAIVVIFELI---HR 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/65 (25%)
		Lig_chan	343..593	CDD:278489	55/315 (17%)
glr-5	NP_505244.1	PBP1_iGluR_delta_like	26..418	CDD:107376	36/176 (20%)
		ANF_receptor	38..377	CDD:279440	18/74 (24%)
		PBP2_iGluR_Kainate	438..819	CDD:270432	77/413 (19%)
		Lig_chan	568..855	CDD:278489	55/317 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810