Protein Alignment Ir7c and glr-3

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 120/646 - (18%)
• Similarity: 225/646 - (34%)
• Gaps: 185/646 - (28%)

  Fly    67 LEDDRVEMTETDTDPPPPSGLTGRPIAIWFLDSLRSYFRLEMYLN-----QLGSPYK-----RNG 121
            :||.|.|:....:...|..|:. ...:|| :|:||...|....:.     :.||.:|     :..
 Worm   271 IEDIRQEIVHKSSIRLPKKGVP-YTTSIW-IDTLRLLIRSMKSIQIWDEPRCGSSWKSGSDIKKR 333

  Fly   122 FFLVIYTGLEDQPMESLKIMFRRLLNMYVLNVNVFLQRDGTVHLYTYYPYGPHHCQSSLPVY--- 183
            ||        :.|:..:                     .|.:|   :.|.| .....:|.||
 Worm   334 FF--------ENPLAGI---------------------SGDLH---WAPSG-ERSNYTLHVYRRT 365

  Fly   184 --YTAFQDLAAPANGFGLTKPLF----PRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIH 242
              :..|.:.::.......::.:.    ..||| :.|..:.::.:...|:|:|     |..|
 Worm   366 LSFQKFAEWSSRTRRIASSEAVVIANSSEKLT-LEGKHLKISVYLEAPFVMI-----TSNG---- 420

  Fly   243 GIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKAR 304
            ..||.   :...:|..:.||..:.:.:|...|....:|.::|::..:..|:.:|.......|..|
 Worm   421 SYEGYCIDLLHKIANILKFTYTIQKVRDNAYGSKESNGKWSGMVGELQRGDADLAVASLTISYGR 485

  Fly   305 SDLMLPSTSYTSFPIVLVVPSGGSISPMGRLTRPFRYI------IWSCILVSLIFGFVLICLL-K 362
            |:::..:..|....|.::..     .|..|.:..|:::      :|.....|.....|.|.:: |
 Worm   486 SEVIDFTVPYMHLGISILFK-----KPRIRDSDWFKFMDPLSTQVWIMTFASYFVVSVAIWIIAK 545

  Fly   363 ITALP------------------GLRNLVLGRRNRLPFMGMW---ASLLGGLALYNPQRNFARYI 406
            |:...                  .|||            ..|   .||:...:...|:....|.:
 Worm   546 ISPYEQFERDEDNGQYKPVDNQFSLRN------------SFWFTVCSLMQQGSELCPRAASTRLL 598

  Fly   407 LVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFH 471
            ..:|....|||.::||..|..:|....|.:||::..::.|   :.:|  ...|:.:.|  |.:|.
 Worm   599 TGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAA---QTKI--KYGTLGRGS--TMSFF 656

  Fly   472 AVLSLE--ESLYRLRDEDDPGITVALLQ---PTVNQFDFRSGPNKRHLTVLPDPLMTAPLTFYMR 531
            ....:|  |.:::|. ...||:.|...:   ..|...|:.                      |:.
 Worm   657 NESKIETYERMWQLM-SSSPGLFVQSSKEGIARVKSSDYA----------------------YLM 698

  Fly   532 PHSYFKRRIDRLIMAMMSSGIV------------ARYRKMYMDRIKRVSKRRNLEPKPLSIWR-- 582
            ..|..:..::|....|...|::            :.||::....|.|:.::..|.......|:
 Worm   699 ESSMLEYAVERDCELMQIGGLIDQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDK 763

  Fly   583 -----------------LSGIF-VCCAGLYLVALIVFILEILTTN-----HRRLRRAFNVI 620
                             :.||| :...||.|.|::| |.|::||.     ..::.|..|||
 Worm   764 SVVCEQPKRKDQDDGESIGGIFIILVVGLVLTAVLV-IFELITTRKPSPAQSQVIRHVNVI 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/64 (22%)
		Lig_chan	343..593	CDD:278489	53/308 (17%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	26/148 (18%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	73/415 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810