Protein Alignment Ir7c and gria3a

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_005165152.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 903
• Species: Danio rerio
• Alignment Length: 647
• Identity: 120/647 - (18%)
• Similarity: 220/647 - (34%)
• Gaps: 188/647 - (29%)

  Fly    64 QFLLEDDRVEMTETDTDPPPP----SGLTGRPIAIWFLDSLRSYFRLEMYLNQLGS--------- 115
            |||...:|::..|.......|    |.||...|.: ..::.|...|..:.:::.||
Zfish   275 QFLQRWERLDEREFPESRSSPLKYTSALTHDAILV-IAEAFRYLRRQRVDISRRGSAGDCLANPA 338

  Fly   116 -PYKRNGFFLVIYTGLEDQPMESLKIMFRRLLNMYVLNVNVFLQRDG-------TVHLYTYYPYG 172
             |:.:         |::.:         |.|..:.|..:...:|.|.       ||.:|...|.|
Zfish   339 VPWSQ---------GIDIE---------RALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKPGG 385

  Fly   173 PHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTN----MHGCEMVVATFEHRPYVIIEDDP 233
            .....     |:..|:....          :..:::||    :....:||.|....|||:.:
Zfish   386 ARKIG-----YWNEFEKFVY----------IVEQQVTNESSSVENRTIVVTTIMEAPYVMYK--- 432

  Fly   234 KTPGGRSIHGIEGLIFRSLAERM-NFTIKLVEQKDKNRG-----EILPDGNF----------TGI 282
                 |:...:||      .:|. .:.:.|..:..|:.|     .|:.||.:          .|:
Zfish   433 -----RNYMQLEG------NDRYEGYCVDLASEIAKHVGIKYKLSIVADGKYGARDPETKTWNGM 486

  Fly   283 LKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP-MGRLTRPFRYIIWSC 346
            :..:|.|..::.......:..|.:::..|..:.|..|.:::.......| :.....|..|.||.|
Zfish   487 VGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 551

  Fly   347 ILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLP------------FMGMWASLLGGLAL---- 395
            |:.:.| |..::..|.....|...:|......:.|            |..:|.||  |..:
Zfish   552 IVFAYI-GVSVVLFLVSRFSPYEWHLDDNEETKDPQTPPDPPNDFGIFNSLWFSL--GAFMQQGC 613

  Fly   396 -YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRT 459
             .:|:....|.:..:|...|||:.::||..|...|....|.|||:| :|.|||..|.    |..|
Zfish   614 DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES-AEDLAKQTEI----AYGT 673

  Fly   460 IFKDSMPTTNF--HAVLSLEESLYRLRDEDDPGITVA------------------LLQPTVNQFD 504
            :  ||..|..|  .:.:::.|.::......:|.:.|.                  ||:.|:|::.
Zfish   674 L--DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYI 736

  Fly   505 FRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRK 558
            .:..|           :|.:....|             ..|..:..::..::.:...||:.:.:.
Zfish   737 EQRKPCDTMKVGGNLDSKGYGVATP-------------KGSALRTPVNLAVLKLSEQGILDKLKN 788

  Fly   559 MY---------MDRIKRVSKRRNLEPKPLSI------------------WRLSGIFVCCAGL 593
            .:         .|...:||...:|...|.:|                  |.|..:|.|...:
Zfish   789 KWWYDKGECGTKDSGSKVSLLTHLTVLPTNISIYHKHHNEFPVAGFTFFWPLFILFTCAQAI 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/77 (18%)
		Lig_chan	343..593	CDD:278489	64/324 (20%)
gria3a	XP_005165152.1	PBP1_iGluR_AMPA_GluR3	28..399	CDD:107382	28/147 (19%)
		ANF_receptor	39..382	CDD:279440	24/125 (19%)
		PBP2_iGluR_AMPA	415..797	CDD:270433	80/418 (19%)
		Lig_chan	547..810	CDD:278489	57/285 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591766
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740