Protein Alignment Ir7c and gria3a

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 705
• Identity: 134/705 - (19%)
• Similarity: 242/705 - (34%)
• Gaps: 215/705 - (30%)

  Fly    64 QFLLEDDRVEMTETDTDPPPP----SGLTGRPIAIWFLDSLRSYFRLEMYLNQLGS--------- 115
            |||...:|::..|.......|    |.||...|.: ..::.|...|..:.:::.||
Zfish   275 QFLQRWERLDEREFPESRSSPLKYTSALTHDAILV-IAEAFRYLRRQRVDISRRGSAGDCLANPA 338

  Fly   116 -PYKRNGFFLVIYTGLEDQPMESLKIMFRRLLNMYVLNVNVFLQRDG-------TVHLYTYYPYG 172
             |:.:         |::.:         |.|..:.|..:...:|.|.       ||.:|...|.|
Zfish   339 VPWSQ---------GIDIE---------RALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKPGG 385

  Fly   173 PHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTN----MHGCEMVVATFEHRPYVIIEDDP 233
            .....     |:..|:....          :..:::||    :....:||.|....|||:.:
Zfish   386 ARKIG-----YWNEFEKFVY----------IVEQQVTNESSSVENRTIVVTTIMEAPYVMYK--- 432

  Fly   234 KTPGGRSIHGIEGLIFRSLAERM-NFTIKLVEQKDKNRG-----EILPDGNF----------TGI 282
                 |:...:||      .:|. .:.:.|..:..|:.|     .|:.||.:          .|:
Zfish   433 -----RNYMQLEG------NDRYEGYCVDLASEIAKHVGIKYKLSIVADGKYGARDPETKTWNGM 486

  Fly   283 LKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP-MGRLTRPFRYIIWSC 346
            :..:|.|..::.......:..|.:::..|..:.|..|.:::.......| :.....|..|.||.|
Zfish   487 VGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 551

  Fly   347 ILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLP------------FMGMWASLLGGLAL---- 395
            |:.:.| |..::..|.....|...:|......:.|            |..:|.||  |..:
Zfish   552 IVFAYI-GVSVVLFLVSRFSPYEWHLDDNEETKDPQTPPDPPNDFGIFNSLWFSL--GAFMQQGC 613

  Fly   396 -YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRT 459
             .:|:....|.:..:|...|||:.::||..|...|....|.|||:| :|.|||..|.    |..|
Zfish   614 DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES-AEDLAKQTEI----AYGT 673

  Fly   460 IFKDSMPTTNF--HAVLSLEESLYRLRDEDDPGITVA------------------LLQPTVNQF- 503
            :  ||..|..|  .:.:::.|.::......:|.:.|.                  ||:.|:|::
Zfish   674 L--DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYI 736

  Fly   504 ----------------------------DFRSGPNKRHLTVLP---------------------- 518
                                        ..||..|   |.||.
Zfish   737 EQRKPCDTMKVGGNLDSKGYGVATPKGSALRSAVN---LAVLKLNEQGLLDKLKNKWWYDKGECG 798

  Fly   519 -----------DPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYR-KMYMDRIKRVSKRR 571
                       .|.::..||....|       ::..::.:...||:.:.: |.:.|:.:..:|..
Zfish   799 SGGGDSKHKARCPTVSLWLTDIRTP-------VNLAVLKLSEQGILDKLKNKWWYDKGECGTKDS 856

  Fly   572 NLEPK--PLSIWRLSGIFVCCAGLYLVALIVFILEILTTNH---RRLRRAFNVIN 621
            ..:.|  .||:..::|:|....|...:|:.|.::|....:|   :||:.|.|..|
Zfish   857 GSKDKTSALSLSNVAGVFYILVGGLGLAMTVALVEFCYKSHQETKRLKLAKNAQN 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/77 (18%)
		Lig_chan	343..592	CDD:459656	68/350 (19%)
gria3a	XP_073805840.1	None