Protein Alignment Ir7c and Grin2d

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 683
• Identity: 136/683 - (19%)
• Similarity: 235/683 - (34%)
• Gaps: 191/683 - (27%)

  Fly    85 SGLTGRPIAIWFLDSLR------SYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIMFR 143
            :|||| |..:||:...:      |....|..|...|:|... |.|.|...|..|.       :.|
Mouse   265 AGLTG-PGYVWFMVGPQLAGGGGSGVPGEPLLLPGGAPLPA-GLFAVRSAGWRDD-------LAR 320

  Fly   144 RLLNMYVLNVNVF------LQRDGTVHLYTYYPYGPHHCQS--------SLPVYYTAF----QDL 190
            |:    ...|.|.      |.||     |.:.|...|.|::        ||..|:...    :|.
Mouse   321 RV----AAGVAVVARGAQALLRD-----YGFLPELGHDCRAQNRTHRGESLHRYFMNITWDNRDY 376

  Fly   191 AAPANGFGLTKPLFPRKLTNMHGCEMV--------------------------------VATFEH 223
            :...:||.:...|....||.....|:|                                |||.|.
Mouse   377 SFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEE 441

  Fly   224 RPYVIIE----------------------------------DDPKTPGGRSIHGIEGLIFRSLAE 254
            ||:||:|                                  |.|: |..|...|....|.:.||.
Mouse   442 RPFVIVEPADPISGTCIRDSVPCRSQLNRTHSLVAPRSPPPDAPR-PEKRCCKGFCIDILKRLAH 505

  Fly   255 RMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPI 319
            .:.|:..|....:...|:.: ||.:.|::..:.....::.......::.||:::..|..:....|
Mouse   506 TIGFSYDLYLVTNGKHGKKI-DGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGI 569

  Fly   320 -VLVVPSGGSISPMGRLT----------RPFRYIIW-----SCILVSLIFGFVLICL-------- 360
             |:|..|.|::||...|.          .|:...:|     .|:.|..:..|:...|
Mouse   570 SVMVARSNGTVSPSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRS 634

  Fly   361 LKITALPGLRNLVLGRRNRLPFMGMWASLL-GGLALYNPQRNFARYILVMWLLQTLILRAAYTGQ 424
            |.....||.....:|:...|    :||.:. ..:.:.||:...::.::::|....:|..|:||..
Mouse   635 LATGKRPGGSTFTIGKSIWL----LWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTAN 695

  Fly   425 LYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAVL--SLEESL------- 480
            |...:...|....:..||     |.:|: .|      ::..|...|..|.  |.|:::
Mouse   696 LAAFMIQEEYVDTVSGLS-----DRKFQ-RP------QEQYPPLKFGTVPNGSTEKNIRSNYPDM 748

  Fly   481 --YRLRDEDDPGITVALLQPTVNQFD------------FRSGPNKRHLTVLPDPLM-TAPLTFYM 530
              |.:| .:.|.:..||.|....:.|            .|.....:.:|:....:. |......:
Mouse   749 HSYMVR-YNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIAL 812

  Fly   531 RPHSYFKRRIDRLIMAMMSSGIVARYRKMYM------DRIKRVSKRRNLEPKPLSIWRLSGIFVC 589
            ...|.:||.||..::..:....:....::::      |:|:.:|.:       |.|..::|:|..
Mouse   813 HKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKIEVMSSK-------LDIDNMAGVFYM 870

  Fly   590 CAGLYLVALIVFILEILTTNHRRLRRAFNVINR 622
            ......::|:||..|.|.  :.|||......:|
Mouse   871 LLVAMGLSLLVFAWEHLV--YWRLRHCLGPTHR 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	18/95 (19%)
		Lig_chan	343..592	CDD:459656	53/292 (18%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:471960	39/167 (23%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	81/435 (19%)