Protein Alignment Ir7c and Grik3

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001074566.1
• Gene: Grik3 / 14807
• MGIID: 95816
• Length: 919
• Species: Mus musculus
• Alignment Length: 492
• Identity: 119/492 - (24%)
• Similarity: 185/492 - (37%)
• Gaps: 113/492 - (22%)

  Fly   192 APANGFGLTK------PLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL--- 247
            :||:|..:|:      |.....|||.   .::|.|....|:|:.....:|..|..  ..||.
Mouse   409 SPADGLNITEVAKGRGPNVTDSLTNR---SLIVTTVLEEPFVMFRKSDRTLYGND--RFEGYCID 468

  Fly   248 IFRSLAERMNFT--IKLVE------QKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKAR 304
            :.:.||..:.|:  |:|||      |.||        |.:.|::|.::|.:.:|.......:..|
Mouse   469 LLKELAHILGFSYEIRLVEDGKYGAQDDK--------GQWNGMVKELIDHKADLAVAPLTITHVR 525

  Fly   305 SDLMLPSTSYTSFPIVLVV--PSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITAL- 366
            ...:..|..:.:..:.::.  |:|.:.|....| .|....||..:|::.:   .:.|:|.:.|.
Mouse   526 EKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFL-NPLSPDIWMYVLLAYL---GVSCVLFVIARF 586

  Fly   367 ------------PGL----RNLVLGRRNRLPFMGMWASLLGGLALYNPQRNFARYILVMWLLQTL 415
                        ||.    .|..|  .|...| ||.:.:..|..|. |:....|.|..:|...||
Mouse   587 SPYEWYDAHPCNPGSEVVENNFTL--LNSFWF-GMGSLMQQGSELM-PKALSTRIIGGIWWFFTL 647

  Fly   416 ILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKD--YEFRILP--ALRTIFKDSMPTT--NFHAVL 474
            |:.::||..|...|....|.|||.|..: |||.  .|:..:.  |..|.||.|..:|  ...|.:
Mouse   648 IIISSYTANLAAFLTVERMESPIDSADD-LAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM 711

  Fly   475 SLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPLMTAPLTFYMRPHSYFKRR 539
            |.:.|  .|...::.||                   :|.||.....||.:....|:...:....:
Mouse   712 SSKPS--ALVKNNEEGI-------------------QRTLTADYALLMESTTIEYITQRNCNLTQ 755

  Fly   540 IDRLIMAMMSSGIVARYRKMYMDRIK------------RVSKRR-----------NLEPKPLSIW 581
            |..||.: ...||.......|.|:|.            .:.|.:           |.|...|.|.
Mouse   756 IGGLIDS-KGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQ 819

  Fly   582 RLSGIF-VCCAGLYLVALIV---FILEILTTNHRRLR 614
            ::.||| |..|||.|..|:.   ||.::..|..|..|
Mouse   820 KIGGIFIVLAAGLVLSVLVAVGEFIYKLRKTAEREQR 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	19/72 (26%)
		Lig_chan	343..592	CDD:459656	71/295 (24%)
Grik3	NP_001074566.1	PBP1_iGluR_Kainate	37..417	CDD:380605	3/7 (43%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	94/411 (23%)