Protein Alignment Ir7c and Gria4

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 469
• Identity: 95/469 - (20%)
• Similarity: 181/469 - (38%)
• Gaps: 108/469 - (23%)

  Fly   216 MVVATFEHRPYVIIEDDPKTPGGRSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRG-----EILP 275
            :||.|....|||:.:.:.:...|...:  ||           :.:.|..:..|:.|     .|:|
Mouse   417 VVVTTIMESPYVMYKKNHEMFEGNDKY--EG-----------YCVDLASEIAKHIGIKYKIAIVP 468

  Fly   276 DGNF----------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSIS 330
            ||.:          .|::..:|.|:..:.......:..|.:::..|..:.|..|.:::.......
Mouse   469 DGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 533

  Fly   331 P-MGRLTRPFRYIIWSCILVSLIFGFVLICLLK-------ITALP--GLRNLVLGRRNRLP---- 381
            | :.....|..|.||.||:.:.|...|::.|:.       .|..|  |..    |..::.|
Mouse   534 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKE----GPSDQPPNEFG 594

  Fly   382 -FMGMWASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKS 440
             |..:|.||  |..:     .:|:....|.:..:|...|||:.::||..|...|....|.|||:|
Mouse   595 IFNSLWFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 657

  Fly   441 LSEVLAKDYEFRILPALRTIFKDSMPTTNF--HAVLSLEESLYRLRDEDDPGI---TVA------ 494
             :|.|||..|.    |..|:  ||..|..|  .:.:::.|.::......:|.:   |.|
Mouse   658 -AEDLAKQTEI----AYGTL--DSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715

  Fly   495 ---------LLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRR 539
                     ||:.|:|::..:..|           :|.:....|             ..|..:..
Mouse   716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATP-------------KGSSLRTP 767

  Fly   540 IDRLIMAMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCAGLYLVALIVF 601
            ::..::.:..:|::.:.: |.:.|:.:...|....:.|  .||:..::|:|....|...:|::|.
Mouse   768 VNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832

  Fly   602 ILEILTTNHRRLRR 615
            ::|....:....:|
Mouse   833 LIEFCYKSRAEAKR 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/76 (18%)
		Lig_chan	343..593	CDD:278489	64/302 (21%)
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	84/416 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846596
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830