Protein Alignment Ir7c and Gria2

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001344853.2
• Gene: Gria2 / 14800
• MGIID: 95809
• Length: 901
• Species: Mus musculus
• Alignment Length: 463
• Identity: 91/463 - (19%)
• Similarity: 176/463 - (38%)
• Gaps: 96/463 - (20%)

  Fly   216 MVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPDG 277
            :||.|....|||:::.:.:...|...:  ||.   :...:|:...|..||.         |:.||
Mouse   416 VVVTTILESPYVMMKKNHEMLEGNERY--EGYCVDLAAEIAKHCGFKYKLT---------IVGDG 469

  Fly   278 NF----------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP- 331
            .:          .|::..:|.|:.::.......:..|.:::..|..:.|..|.:::.......|
Mouse   470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534

  Fly   332 MGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALP---GLRNLVLGRRNRLP--------FMGM 385
            :.....|..|.||.||:.:.| |..::..|.....|   .......||..:..        |..:
Mouse   535 VFSFLDPLAYEIWMCIVFAYI-GVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSL 598

  Fly   386 WASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVL 445
            |.||  |..:     .:|:....|.:..:|...|||:.::||..|...|....|.|||:| :|.|
Mouse   599 WFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES-AEDL 660

  Fly   446 AKDYE--------------FR-----ILPALRTIFKDSMPTTNFHAVLSLEESLYRLRDEDDPGI 491
            :|..|              ||     :...:.|..:.:.|:.   .|.:..|.:.|:|  ...|.
Mouse   661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV---FVRTTAEGVARVR--KSKGK 720

  Fly   492 TVALLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIM 545
            ...||:.|:|::..:..|           :|.:....|             ..|..:..::..::
Mouse   721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATP-------------KGSSLRTPVNLAVL 772

  Fly   546 AMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCAGLYLVALIVFILEILT 607
            .:...|::.:.: |.:.|:.:..:|....:.|  .||:..::|:|....|...:|::|.::|...
Mouse   773 KLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 837

  Fly   608 TNHRRLRR 615
            .:....:|
Mouse   838 KSRAEAKR 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/74 (19%)
		Lig_chan	343..593	CDD:278489	60/298 (20%)
Gria2	NP_001344853.2	PBP1_iGluR_AMPA_GluR2	28..398	CDD:380612
		PBP2_iGluR_AMPA	413..794	CDD:270433	80/410 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846631
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830