DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir7c and Grik4

DIOPT Version :9

Sequence 1:NP_001245572.1 Gene:Ir7c / 31692 FlyBaseID:FBgn0029966 Length:625 Species:Drosophila melanogaster
Sequence 2:NP_780690.2 Gene:Grik4 / 110637 MGIID:95817 Length:956 Species:Mus musculus


Alignment Length:458 Identity:101/458 - (22%)
Similarity:189/458 - (41%) Gaps:65/458 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 ANGFGLTKPLFPRKLT-NMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL---IFRSLAE 254
            |.|..:...|:...:: ::....:||.|....||::::.:.:...|...:  ||.   :.:.|||
Mouse   395 AEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQEMEGNDRY--EGFCVDMLKELAE 457

  Fly   255 --RMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSF 317
              |.|:.|:||  .|...|....:|.:||::..::..:.:|.......:..|..::..|..:.:.
Mouse   458 ILRFNYKIRLV--GDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTL 520

  Fly   318 PIVLVVPSGGSISPMGR------LTRPFRYIIWSCILVS-LIFGFVLICLLKIT---------AL 366
            .|.::..     ..|||      ...||...:|..:|:: |....||..:.::|         ..
Mouse   521 GISILYR-----VHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCA 580

  Fly   367 PGLRNLVLGRRNRLPFMG--MWASLLGGL----ALYNPQRNFARYILVMWLLQTLILRAAYTGQL 425
            .|..||::.:.:    :|  :|.. :||.    :...|:....|.:..:|...|||:.::||..|
Mouse   581 QGRCNLLVNQYS----LGNSLWFP-VGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANL 640

  Fly   426 YLLLQDVEMRSPIKS---LSEVLAKDYEFRILPALRTIFKDSMPTT-----NFH-------AVLS 475
            ...|....|..||:|   |::..|.:|......:..|.|::|...|     |:.       .|.|
Mouse   641 AAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKS 705

  Fly   476 LEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPLMTAPLTFYMRPHSYFKRRI 540
            .||.:.|:.:.:    ...||:.|:|::..:...|   ||.:...|.|......|...|.|:...
Mouse   706 TEEGIARVLNSN----YAFLLESTMNEYYRQRNCN---LTQIGGLLDTKGYGIGMPVGSVFRDEF 763

  Fly   541 DRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEI 605
            |..|:.:..:..:...::.:.:..| ..|..:...|.|.:..:.||||......:||:.:.:||.
Mouse   764 DLAILQLQENNRLEILKRKWWEGGK-CPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEF 827

  Fly   606 LTT 608
            |.|
Mouse   828 LWT 830

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7cNP_001245572.1 Lig_chan-Glu_bd 225..287 CDD:214911 18/66 (27%)
Lig_chan 343..593 CDD:278489 62/280 (22%)
Grik4NP_780690.2 Periplasmic_Binding_Protein_type1 24..402 CDD:385651 2/6 (33%)
PBP2_iGluR_kainate_KA1 415..785 CDD:270442 84/390 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 931..956
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846213
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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