DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir7c and grid2

DIOPT Version :9

Sequence 1:NP_001245572.1 Gene:Ir7c / 31692 FlyBaseID:FBgn0029966 Length:625 Species:Drosophila melanogaster
Sequence 2:XP_031759030.1 Gene:grid2 / 100487676 XenbaseID:XB-GENE-955038 Length:1007 Species:Xenopus tropicalis


Alignment Length:484 Identity:92/484 - (19%)
Similarity:169/484 - (34%) Gaps:135/484 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 GLTKPLFPRKL-TNMHGCEMVVATFEHRPYVIIEDD----PKTPGGRSIHGIEGLIFRSLAERMN 257
            ||...|..||| .||.|..:.|||....|:|::.::    ||...|.||.     :..:|:..:.
 Frog   424 GLNGSLTDRKLENNMRGVVLRVATVLEEPFVMVSENVLGKPKKYQGFSID-----VLDALSSYLG 483

  Fly   258 FTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLV 322
            |..::....|...|....||::.|::..::....::.......:..|.:::..:|.|..:.:.::
 Frog   484 FKYEIYVASDHKYGSPQADGSWNGLIGELLLKRADMGISALTITPDRENVVDFTTRYMDYSVGVL 548

  Fly   323 VPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLPFMGMWA 387
            :........|.....||...:|:||..:::...:|:.||.....|.|:            ||...
 Frog   549 LRKAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQ------------MGSMT 601

  Fly   388 SLLGGLALYN----------------PQRNFA-RYILVMWLLQTLILRAAYTGQLYLLLQDVEMR 435
            |    ..|||                |....| |.::..|.|..||:.::||..|...|....:.
 Frog   602 S----TTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIE 662

  Fly   436 SPIKSLSEVLAKD------------YEFRILPALRTIFKDSMPTTNFHAV-------LSLEESL- 480
            |.|:||.::..:.            ||...:..:....:|||.:..:..:       .:::||| 
 Frog   663 SSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINRSNGSENNVQESLE 727

  Fly   481 ---------------------YRLRDED-----------DPGITVALLQPTVNQFDFRSGPNKRH 513
                                 ..:.|:|           |.|..:||          :.|...|.
 Frog   728 GIQKVKHGNYAFVWDAAVLEYIAINDQDCSFYTVGNTIADRGYGIAL----------QHGSPYRD 782

  Fly   514 LTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPK-- 576
            :                     |.:|    |:.:..:|.:...:..:..|..:.....:::.|  
 Frog   783 I---------------------FSQR----ILELQQNGDMDILKHKWWPRNGQCELHSSMDTKQK 822

  Fly   577 --PLSIWRLSGIF-VCCAGLYLVALIVFI 602
              .|.|...||:| :..||:.|...|..:
 Frog   823 GSSLDIKSFSGVFCILAAGIVLSCFIAMV 851

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7cNP_001245572.1 Lig_chan-Glu_bd 225..287 CDD:214911 14/65 (22%)
Lig_chan 343..593 CDD:278489 57/323 (18%)
grid2XP_031759030.1 Periplasmic_Binding_Protein_type1 28..429 CDD:415822 2/4 (50%)
PBP2_iGluR_delta_2 440..806 CDD:270449 73/421 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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