Protein Alignment Ir7b and grik5

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 747
• Identity: 130/747 - (17%)
• Similarity: 229/747 - (30%)
• Gaps: 305/747 - (40%)

  Fly    37 SEMGRFKTLYIYTHTNSQSTGGHLEELLDQVLMIV---------PNNLQARR---LLLQQSMEYK 89
            ||:|.....|.|..|........|::::|:...||         |..|:..|   |..::..:..
Zfish   244 SELGMTSAFYKYILTTMDFPLLWLDDIVDEQSNIVGFSMFNTTHPFYLEFIRSLNLSWREGCDIN 308

  Fly    90 PYVHAVL--ALVDGLPSLSAIYARIRATQDLSHTLIYMSMPTDAYGEEMQATLRFLWR--LSVLN 150
            ||....|  ||:     ..|::..:.|.|:|:.:......|       :..|...:|:  .|::|
Zfish   309 PYPGPALSSALL-----FDAVHVVVSAVQELNRSQEIGVKP-------LSCTSPQIWQHGTSLMN 361

  Fly   151 VGVVLRPPGDHILMVSY------FPFSALHGCQVISANVVNRYQVGTKRWASQDYFPSKLGNFY- 208
                      ::.||.|      ..|::.......:.:::.:::.|.|          ::|.:|
Zfish   362 ----------YLRMVEYDGLTGRVEFNSKGQRTNYTLHILEKHRGGHK----------EIGIWYS 406

  Fly   209 -GCLLTCATWEDM-------------------PYLVWRP-----DGSGSFVGIEGALLQFMAENL 248
             ..||..:|..|:                   ||::.:.     :|:..:.|....:|:.:::.|
Zfish   407 NNTLLMNSTSLDINVSETLANKSLIITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDIL 471

  Fly   249 NFTV-------GLY--------WMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEI 298
            .||.       |||        |            :|.: .|:....||.::..|.........|
Zfish   472 KFTYRIKLVDDGLYGAPEPNGSW------------TGMV-GELINRKADLAVAAFTITSEREKVI 523

  Fly   299 PYSQSTYYFMS---------HIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLV 354
            .:|:.   ||:         ||       .....|.....||:|.:|..:.|..:....:|.|..
Zfish   524 DFSKP---FMTLGISILYRVHI-------GRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLSA 578

  Fly   355 R-----W-------RHHHELPRNPYYELLVLTMGGNLEDRW-------------VPQRFPSRLVL 394
            |     |       |...:|..|.|      |:|.:|   |             :|:...:|.|.
Zfish   579 RLSPYEWYNPHPCLRERRDLLENQY------TLGNSL---WFPVGGFMQQGSEIMPRALSTRCVS 634

  Fly   395 LTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNEARILASLPELRPEQ 459
            ..|...||::.|.|.:.                    ||...|:|..||
Zfish   635 GVWWAFTLIIISSYTAN--------------------LAAFLTVQRMEV---------------- 663

  Fly   460 LVYLEGSELQSFPALAQQSGSSARVAILTPYEYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRR 524
                   .::|...||.|:...              :..:|..|.....:..|..|     |.|.
Zfish   664 -------PIESPDDLADQTNIQ--------------YGTIHGGSTMTFFMNSRYQT-----YQRM 702

  Fly   525 HSHLVGVLNKQIQHAHTHGFLEHWTRQYVSAVDEKDESVARIASTSY-----STLD--------- 575
            .:::                   :::|....|...:|.:||:.::.|     ||::
Zfish   703 WNYM-------------------YSKQPSVFVKSTEEGIARVVNSKYAFLLESTMNEYHRSLNCN 748

  Fly   576 -------------GID---GDPSLSE----------------------------SEEDQQVAPVR 596
                         ||.   |.|...|                            .|||.     |
Zfish   749 LTQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGGKCPKEEDH-----R 808

  Fly   597 QNVLSMRELAALFWLILWANLGAVVVFVLELL 628
            ...|.|..:..:|.:::...:.||.|.|:|.:
Zfish   809 AKGLGMENIGGIFVVLICGLIIAVFVAVMEFV 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	36..414	CDD:380616	38/201 (19%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:473866	78/482 (16%)