Protein Alignment Ir7b and gria1a

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_991161.1
• Gene: gria1a / 798689
• ZFINID: ZDB-GENE-020125-1
• Length: 914
• Species: Danio rerio
• Alignment Length: 772
• Identity: 133/772 - (17%)
• Similarity: 252/772 - (32%)
• Gaps: 249/772 - (32%)

  Fly    26 LAEALAQVVANSEMGRFKTLYIYTHTN---------------SQSTGGHLEELLDQVLMIVPNNL 75
            |...|.:::   |:|:....|.|...|               :..||..|....|      ||..
Zfish   208 LTSILKKII---ELGKNVKSYHYILANLGFLDIDLTEFKKGEANVTGFQLVNYAD------PNVS 263

  Fly    76 QARRLLLQQSMEYK-----------PYVHAVLALVDGLPSLSAIYARIRATQ-DLS---HTLIYM 125
            :.    :||.||:.           .|..|:  ..||:..:|..:..:|..: |:|   :....:
Zfish   264 RT----VQQWMEFDNKDAKVPKRRLKYTGAL--TYDGVKVMSTAFQNLRRQRIDISRRGNAGECL 322

  Fly   126 SMPTDAYGE--EMQATL-------------------RFLWRLSVLNVGVVLRPPG---------- 159
            :.|...:|:  ::|..|                   |..:.:||:.    |||.|
Zfish   323 ANPPAPWGQGIDIQRALQQVRIEGLTGHIQFNEKGRRTNYSISVME----LRPTGPKKVGYWNED 383

  Fly   160 -DHILMVSYFPFS-ALHGCQVISANVVNRYQVGTKRWASQDYFPSKLGNFYGCLLTCATWEDMPY 222
             ..:...:|.|.| ..:|.|       ||..:.|                        |..:.||
Zfish   384 EKFVSTAAYMPGSNETYGLQ-------NRTYIVT------------------------TILESPY 417

  Fly   223 LVWRPDGSGSFVG---IEGALLQFMAENLNFTVGLYWMNKEEVLA----------TFDESGRIFD 274
            ::.:.:.. .|.|   .||..::..|| :...||.:::.|  ::|          |...:|.:.:
Zfish   418 VMLKKNHE-HFTGNDKYEGYCVELAAE-IAKHVGYHYILK--IVADGKYGARDAETMMWNGMVGE 478

  Fly   275 EIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMS---HIMLVTNLQSAYSAYEKLSFPFTPLLW 336
            .::| .||.::............|.:|:.   |||   .||:....:|....:..|. |....:|
Zfish   479 LVYG-KADVAVAPLTITLVREEVIDFSKP---FMSLGISIMIKKPTKSKPGVFSFLD-PLAYEIW 538

  Fly   337 RAIGLVLILACLLLMLLVRWRHH-----------HELPRNP------------------------ 366
            ..|....|...::|.|:.|:..:           .|.|..|
Zfish   539 MCIVFAYIGVSVVLFLVSRFSPYEWHADDCEDGAEENPNQPSSSSAQPGQNQQNQNQQSQEQTNE 603

  Fly   367 --YYELLVLTMGGNLEDRW--VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQT 427
              .:..|..::|..::...  .|:....|:|...|.|.||::.|.|.:.:...|..:...:|.::
Zfish   604 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 668

  Fly   428 ISEVLAQ----HFTIQLAEVNE----------ARILASLPELRPEQLVYLEGSELQSFPALAQQS 478
            ..::..|    :.|:......|          .::.:.:....|.  |:::.:: :....:.:..
Zfish   669 AEDLAKQTEIAYGTLDAGSTKEFFRRSKIAVFEKMWSYMKSADPS--VFVKTTD-EGVMRVRKSK 730

  Fly   479 GSSARVAILTPYEYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHG 543
            |..|.:...|..||....:....|.     |...:.::.......:.|.|...:|..:...:..|
Zfish   731 GKYAYLLESTMNEYIEQRKPCDTMK-----VGGNLDSKGYGIATPKGSPLRNPVNLAVLKLNEQG 790

  Fly   544 FLEHWTRQY--------VSAVDEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVL 600
            .|:....::        ....|.||::.|                                   |
Zfish   791 LLDKLKNKWWYDKGECGSGGGDSKDKTSA-----------------------------------L 820

  Fly   601 SMRELAALFWLILWANLG-AVVVFVLELLLPRIKLRKILRKMKSDIKKQI--SKLVR 654
            |:..:|.:|:::: ..|| |::|.::|..   .|.|...|:||..|...:  |.|.|
Zfish   821 SLSNVAGVFYILI-GGLGLAMLVALVEFC---YKSRTESRRMKQSINDAMHCSTLTR 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
gria1a	NP_991161.1	Periplasmic_Binding_Protein_type1	26..390	CDD:471960	36/200 (18%)
		PBP2_iGluR_AMPA_GluR1	404..806	CDD:270447	70/442 (16%)
		Lig_chan	536..835	CDD:459656	47/342 (14%)