Protein Alignment Ir7b and grik4

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 735
• Identity: 131/735 - (17%)
• Similarity: 256/735 - (34%)
• Gaps: 193/735 - (26%)

  Fly    25 DLAEALAQVVAN--SEMGRFKTLYIYTHTNSQSTGGHLEELLDQVLMIVPNNLQARR-------- 79
            |....::.|:..  ||:|.....|.|..|:.:.:...|::|.||.:.||..::..|.
Zfish   218 DANATMSHVILERASELGMLSVYYTYILTSLEFSLLRLDDLADQRVNIVGFSVFNRTHPFFQDFV 282

  Fly    80 LLL----QQSMEYKPYVHAVLA---LVDGLPSLSAIYARIRATQDLSHT-LIYMSMPTDAYGEEM 136
            |.|    |::.::.|:....|:   |.|.:.::.|....:..:|::..| |...|.....:|..:
Zfish   283 LSLNRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNVGATQLSCKSSKIWEHGTSL 347

  Fly   137 QATLRFLWRLSVLNVGVVLRPPGDHILMVSYFPFSALHGCQVISANVVNRYQVGTKRWASQD--- 198
            ...||.: .|..|...:.....|..          :.:..:::..:.....|:|  :|.|:.
Zfish   348 MNYLRMV-ELEGLTGHIEFNSKGQR----------SNYALRIMQNSRDGLRQIG--QWHSEQGLS 399

  Fly   199 ---YFPS--KLGNFYGCLLTCATWEDMPYLVWRP-----DGSGSFVGIEGALLQFMAENLNFTV- 252
               ..||  .....:...||..|..:.||::.|.     :|:..:.|....:|:.:|:.|.|..
Zfish   400 MERKLPSLNVTDTLFNTTLTITTILENPYVMLRANHQELEGNDRYEGFCVDMLKELADILKFKYR 464

  Fly   253 ------GLY--------WMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQS 303
                  |:|        |            :|.: .|:....||.::............|.:|:.
Zfish   465 IRLVGDGVYGVPGANGTW------------TGMV-GELISRKADLAVAALTITAEREKVIDFSKP 516

  Fly   304 TYYFMSHIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVR-----WRHHH--- 360
            .......||...:: .....|.....||:|.:|..:.|..:....:|.|:.|     |.:.|
Zfish   517 FMTLGISIMYRVHI-GRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYNPHPCL 580

  Fly   361 ----ELPRNPYYELLVLTMGGNLEDRW-------------VPQRFPSRLVLLTWLFATLVLRSGY 408
                .|..|.|      ::|.:.   |             .|:...:|.|...|...||::.|.|
Zfish   581 KGRCSLLINQY------SLGNSF---WFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSY 636

  Fly   409 QSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSF-- 471
            .:.:...|.......|.:::.: ||....|:...::..           ..:.:.:.|..|::
Zfish   637 TANLAAFLTVQRMEVPIESVDD-LADQTAIEYGTMHGG-----------STMTFFQNSRYQTYQR 689

  Fly   472 ---------PALAQQSGSSARVAIL-TPYEYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRRHS 526
                     |::..:|.......:| :.|.|.                   :.:....:|.:|:.
Zfish   690 MWNFMYSKQPSVFVKSTEEGIARVLNSNYAYL-------------------LESTMNEYYRQRNC 735

  Fly   527 HLVGVLNKQIQHAHTHGFLEHWTRQY-----VSAV--DEKDESVARIASTSYSTL------DGID 578
            :|..:          .|.|:  |:.|     :.:|  ||.|.::.|:...:...:      ||
Zfish   736 NLTQI----------GGLLD--TKGYGIGMPLGSVYRDEFDLAILRLQEENRLEILKRKWWDG-- 786

  Fly   579 GDPSLSESEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVVVFVLELL-----LPRIKL---R 635
               .....|||.     |...|.|..:..:|.:::...|.|:.:.|||.:     .|..:|   .
Zfish   787 ---GKCPKEEDH-----RAKGLGMENIGGIFVVLVCGLLVAIFMAVLEFVWMLRHTPGTELSVCE 843

  Fly   636 KILRKMKSDIKKQISKLVRK 655
            ::||:::..:..|.|..:|:
Zfish   844 EMLRELQGIVLCQDSLQLRR 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	37/195 (19%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	68/425 (16%)