Protein Alignment Ir7b and Grik

DIOPT Version :9

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 116/694 - (16%)
• Similarity: 234/694 - (33%)
• Gaps: 232/694 - (33%)

  Fly    48 YTHTNSQSTGGHLEELLDQVLMIVPNNLQARRL--LLQQSME-----YKPYVHAVLALVDGLPSL 105
            |.|..:..||         :.::.|::.|.:.:  .|.:|.|     ..|..:::..:.||:..|
  Fly   257 YQHAGTNITG---------LRLVSPDSEQVQEVAKALYESEEPFQNVSCPLTNSMALVYDGVQLL 312

  Fly   106 SAIYARIR-----------ATQDLSHTLI-YMSMPT----------DAYGEEMQATLRFLWRLSV 148
            :..|..:.           :..|..:||: ||...|          |..|      ||..::|.|
  Fly   313 AETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEG------LRTDFKLEV 371

  Fly   149 LNVGVVLRPPGDHILMVSYFPFSALHGCQVISANVVNRYQVGTKRWASQDYFPS----------- 202
            :.:                    |:.|.|.|.            :|:.:|.|..
  Fly   372 IEL--------------------AVSGMQKIG------------QWSGEDGFQENRPAPAHSLEP 404

  Fly   203 ---KLGNFYGCLLTCATWEDMPYLVWRP-----DGSGSFVGIEGALLQFMAENLNFTVGLYWMNK 259
               .|.|....::|..:   .||.:.:.     :|:..|.|....|:..:::.|.|:  ..|..:
  Fly   405 DMRSLVNKSFVVITAIS---EPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFS--YTWRLQ 464

  Fly   260 EE-----VLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMS---HIMLVTN 316
            |:     :.....|...:..||....||..:..........|.:.:   |..|||   .|:....
  Fly   465 EDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDF---TIPFMSLGIGILFRKP 526

  Fly   317 LQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVR-----WRHHHELPRNP--------YY 368
            ::.....:..:| ||:..:|..:||..:...:.:.:|.|     |.:.:.....|        :.
  Fly   527 MKEPPKLFSFMS-PFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFA 590

  Fly   369 ELLVLTMGGNLE--DRWVPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEV 431
            ..|..::|..|:  ....|:.:.:|.|..:|.|.||:|.|.|.:.:...|..::...|
  Fly   591 NCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTP------- 648

  Fly   432 LAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSFPALAQQSGS---SARVAILTPYEYF 493
                       :|:|                         ..|::..|.   .|::...|    |
  Fly   649 -----------INDA-------------------------DDLSKNKGGVNYGAKIGGAT----F 673

  Fly   494 GYFRKV-HPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQ----IQHAHTHGFLEHWTRQYV 553
            .:|::. :|..:|::            .::|.:...:...|::    :::::....:|..|.:|:
  Fly   674 NFFKESNYPTYQRMY------------EFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYI 726

  Fly   554 -----------SAVDEKDESVARIASTSY-STL---------DGI------------DGDPSLSE 585
                       :.:|||...:|...:..| .||         .|:            .|..:.|:
  Fly   727 TERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSD 791

  Fly   586 SEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVVVFVLELLL 629
            ::||....     .|.:..|..:|.::...:...:.|.:||::|
  Fly   792 ADEDSGAV-----ALEISNLGGVFLVMGVGSFFGIFVSLLEMVL 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	32/180 (18%)
		ANF_receptor	53..374	CDD:279440	26/131 (20%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	71/437 (16%)
		Lig_chan	543..816	CDD:278489	52/336 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840