Protein Alignment Ir7b and Nmdar1

DIOPT Version :9

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 814
• Identity: 134/814 - (16%)
• Similarity: 258/814 - (31%)
• Gaps: 252/814 - (30%)

  Fly     4 WLYILSCCSLVASTMESSSDWDLAEALAQVVANSEMGRFKTL--YIYTHTNSQST---------- 56
            ||.:||..:.....:..|||.|         ..:.:|||:|.  ..|...:.::|
  Fly   164 WLEMLSHFAYTKVIIIHSSDTD---------GRAILGRFQTTSQTYYDDVDVRATVELIVEFEPK 219

  Fly    57 -GGHLEELLD------QVLMIVPNNLQARRLLLQQSMEYKPYVHAVLALV-----------DGLP 103
             ....|.|:|      :|.::..:...| :::.:.:.||.......:.:|           ||:.
  Fly   220 LESFTEHLIDMKTAQSRVYLMYASTEDA-QVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVL 283

  Fly   104 SL-------------SAIYARIRATQDLSHTLIYMSMPTDAYGE---EMQATLRFLWRLSVLNV- 151
            .|             .::|....|.:::.........|.|. |:   ..::..|....|...|:
  Fly   284 GLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDC-GDSAVNWESGKRLFQYLKSRNIT 347

  Fly   152 ----GVVLRPPGDHILMVSYFPFSALHGCQVISANVVNRYQVGTKRWA-------SQDYFPSKL- 204
                .|.....||.|    |..:..::..:....:||.::...:.|..       |:..:|.|.
  Fly   348 GETGQVAFDDNGDRI----YAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQR 408

  Fly   205 ----GNFYGCLLTCATWEDMPYLVWRPDGSGSF------------------------VGIEGALL 241
                |......|...|.|:.|::..|..|...|                        .|....||
  Fly   409 RKPEGIMIPTHLRLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLL 473

  Fly   242 QFMAENLNFT----------VGLYWM-NKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAG 295
            ..:::.:|||          .|.|.: |....:....|...:..|:....||..:......|...
  Fly   474 IELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERA 538

  Fly   296 SEIPYSQSTYYFMSHIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVRWR--H 358
            ..|.:|:...|  ..|.::....|..|.......||:..||..:.:.:.:..|:|.||.|:.  .
  Fly   539 EYIEFSKPFKY--QGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFG 601

  Fly   359 HHELPRNPYYELLVLTMGGNLEDRW-----------VPQRFPSRLVLLTWLFATLVLRSGYQSGM 412
            ..:|..:...|...|.:...:...|           .|:.|.:|::.:.|....:::.:.|.:.:
  Fly   602 RFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANL 666

  Fly   413 YQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSFPALAQQ 477
            ...|..:.    |:|           :|:.:|:||:..::..|                 ..|..
  Fly   667 AAFLVLER----PKT-----------KLSGINDARLRNTMENL-----------------TCATV 699

  Fly   478 SGSSARVAILTPYEYFGYFRKVHPMSRRLHLVRERIY---------------------TQQLAFY 521
            .|||..:          |||:...:|.....:....|                     :.:|.:.
  Fly   700 KGSSVDM----------YFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYE 754

  Fly   522 VRRHSHLV-----------GV-LNK----------QIQHAHTHGFLEHWTRQYVSAVDEKDESVA 564
            ..:...||           |: |.|          .|...|..||:|...:|::..
  Fly   755 ASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFH--------- 810

  Fly   565 RIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVVVFVLELLL 629
                               ...:::.::.....|.|.::.:|.:|.|:.....|.|.:.::|::.
  Fly   811 -------------------GHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIY 856

  Fly   630 PRIKLRKILR---------KMKSDIKKQISKLVR 654
            .:.:::|..|         |.:..|:|:  |.:|
  Fly   857 KKHQVKKQKRLDIARHAADKWRGTIEKR--KTIR 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	42/255 (16%)
		ANF_receptor	58..371	CDD:279440	38/221 (17%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	74/472 (16%)
		HisJ	451..>558	CDD:223904	18/108 (17%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	26/136 (19%)
		Lig_chan	575..838	CDD:278489	49/332 (15%)
		CaM_bdg_C0	854..882	CDD:287524	3/27 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840