Protein Alignment Ir7b and gria1b

DIOPT Version :9

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 646
• Identity: 102/646 - (15%)
• Similarity: 175/646 - (27%)
• Gaps: 292/646 - (45%)

  Fly   202 SKLGNFYGCLLTCATWEDMPYLVWRPDGSGSFVGIEGALLQFMAENL-------------NFTVG 253
            |:.||...||..       |...|     |..:.|:.||.|...|.|             ||||.
Zfish   313 SRRGNAGECLAN-------PPAPW-----GQGIDIQRALQQVQFEGLTGHVQFNDKGHRTNFTVS 365

  Fly   254 L------------YWMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYY 306
            :            ||..:|:.::|...| .:.:|.||      |....:..:...|.||   ...
Zfish   366 VMEFGPSGPKKVGYWNQREKYVSTATYS-NMLNETFG------LQNRTYVVTTILEAPY---VML 420

  Fly   307 FMSHIMLVTNLQSAYSAY----------------------------------------------- 324
            ..:|..||.|  ..|..|
Zfish   421 KKNHEQLVGN--DKYEGYCVELAAEIAKHVGYSYRLELVGDGKYGARDAETMMWNGMVGELVYGK 483

  Fly   325 ---------------EKLSF--PFTPL--------------------------LWRAIGLVLILA 346
                           |.:.|  ||..|                          :|..|....|..
Zfish   484 ADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGV 548

  Fly   347 CLLLMLLVR-----W----------RHHHELPRNP----------------------------YY 368
            .::|.|:.|     |          :.:...|.:|                            .:
Zfish   549 SVVLFLVSRFSPYEWHADDEEETADQQNQNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIF 613

  Fly   369 ELLVLTMGGNLEDRW--VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEV 431
            ..|..::|..::...  .|:....|:|...|.|.||::.|.|.:.:...|..:...:|.::..::
Zfish   614 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 678

  Fly   432 LAQHFTIQLAEVNEARILASLPELRPEQLVY--LEGSELQSFPALAQQSGSSARVAILTPYEYFG 494
            ..|                       .::.|  |:|...:.|       ...:::|:..  :.:.
Zfish   679 AKQ-----------------------TEIAYGTLDGGSTKEF-------FRRSKIAVFE--KMWS 711

  Fly   495 YFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGFLEHWTRQYVSA---- 555
            |.:...|                ..|.......:|.|...:.::|:   .||....:|:..
Zfish   712 YMKSAEP----------------TVFVKTTDEGVVRVRKSKGKYAY---LLESTMNEYIEQRKPC 757

  Fly   556 --------VDEKDESVAR--------------IASTSYSTLD-------------GIDGDPSLSE 585
                    :|.|...||.              :.......||             |..|..|..:
Zfish   758 DTMKVGGNLDSKGYGVATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDK 822

  Fly   586 SEEDQQVAPVRQNVLSMRELAALFWLILWANLG-AVVVFVLELLLPRIKLRKILRKMKSDI 645
            :           :.||:..:|.:|:::: ..|| |::|.::|..   .|.|...|:||..|
Zfish   823 T-----------SALSLSNVAGVFYILI-GGLGLAMLVALVEFC---YKSRIESRRMKQII 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..387	CDD:107385	21/85 (25%)
		ANF_receptor	41..368	CDD:279440	18/66 (27%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	57/463 (12%)
		Lig_chan	536..842	CDD:278489	50/368 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930