Protein Alignment Ir7b and Grik3

DIOPT Version :9

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001106187.1
• Gene: Grik3 / 298521
• RGDID: 71027
• Length: 919
• Species: Rattus norvegicus
• Alignment Length: 705
• Identity: 126/705 - (17%)
• Similarity: 237/705 - (33%)
• Gaps: 238/705 - (33%)

  Fly    85 SMEYKPYVHAVLAL-------VDGLPSLSAI-----YARIRATQDLSHTLIYMSMPTDA------ 131
            :::.:||.::.:.|       ||. |.:|||     ..|::|.......|:...|.|||
  Rat   266 ALDLEPYRYSGVNLTGFRILNVDN-PHVSAIVEKWSMERLQAAPRAESGLLDGVMMTDAALLYDA 329

  Fly   132 -------YGEEMQATLRFL-------WRLSVLNVGVVLRPPGDHILMVSYFPFSALHG------- 175
                   |....|.|:..|       ||..           |..:..:....:..|.|
  Rat   330 VHIVSVCYQRAPQMTVNSLQCHRHKAWRFG-----------GRFMNFIKEAQWEGLTGRIVFNKT 383

  Fly   176 --------CQVISANVVNRYQVGTKRWASQDYF----------PSKLGNFYGCLLTCATWEDMPY 222
                    ..:||.......:||.  |:..|..          |:...:.....|...|..:.|:
  Rat   384 SGLRTDFDLDIISLKEDGLEKVGV--WSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTLLEEPF 446

  Fly   223 LVWRPD-----GSGSFVGIEGALLQFMAENLNFTVGLYWMNKEEVLATFDESGR---IFDEIFGH 279
            :::|..     |:..|.|....||:.:|..|.|:..:..:...:..|. |:.|:   :..|:..|
  Rat   447 VMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQ-DDKGQWNGMVKELIDH 510

  Fly   280 HADFSLGGF---HFKPSA----------GSEIPY------SQSTYYFMSHIMLVTNLQSAYSAYE 325
            .||.::...   |.:..|          |..|.|      :.|.:.|::
  Rat   511 KADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLN---------------- 559

  Fly   326 KLSFPFTPLLWRAIGLVLI-LACLLLMLL----VRWRHHHELPRNPYYELL-------------- 371
                |.:|.:|..:.|..: ::|:|.::.    ..|...|  |.||..|::
  Rat   560 ----PLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAH--PCNPGSEVVENNFTLLNSFWFGM 618

  Fly   372 --VLTMGGNLEDRWVPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQ 434
              ::..|..|    :|:...:|::...|.|.||::.|.|.:.:...|..:...:|..:..: ||:
  Rat   619 GSLMQQGSEL----MPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADD-LAK 678

  Fly   435 HFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFGYFRKV 499
            ...|:...|.:.           ..:.:.:.|::.:|
  Rat   679 QTKIEYGAVKDG-----------ATMTFFKKSKISTF---------------------------- 704

  Fly   500 HPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGF---LEHWTRQYVSAVDEKDE 561
                       |:::    ||...:.|.||....:.||...|..:   :|..|.:|::   :::.
  Rat   705 -----------EKMW----AFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYIT---QRNC 751

  Fly   562 SVARIASTSYSTLDGID---GDP--------SLSESEEDQ-----------QVAPVRQN----VL 600
            ::.:|.....|...||.   |.|        .|...|||:           ...|..:|    .|
  Rat   752 NLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASAL 816

  Fly   601 SMRELAALFWLILWANLG-AVVVFVLELLLPRIKLRKILRKMKSDIKKQISKLVR 654
            .::::..:| ::|.|.|. :|:|.|.|.:   .||||...:.:......::..:|
  Rat   817 GIQKIGGIF-IVLAAGLVLSVLVAVGEFI---YKLRKTAEREQRSFCSTVADEIR 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
Grik3	NP_001106187.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	31/164 (19%)
		ANF_receptor	55..398	CDD:279440	27/143 (19%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	78/452 (17%)
		Lig_chan	564..832	CDD:278489	56/332 (17%)
		Glutamate binding	690..692		0/12 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350185
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840