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Protein Alignment Ir7b and Gria2

DIOPT Version :9

Sequence 1:	NP_572410.2	Gene:	Ir7b / 31690	FlyBaseID:	FBgn0029965	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	803	Identity:	150/803 - (18%)
Similarity:	251/803 - (31%)	Gaps:	271/803 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DLAEALAQVVANSEMGRFKTLYIYTHTNSQSTGGHLEELLD-------QVLMIVPNNL------- 75
            ||..||..::...:..:|  .|:|......||   |:.:||       ||..|...|:
  Rat   131 DLKGALLSLIEYYQWDKF--AYLYDSDRGLST---LQAVLDSAAEKKWQVTAINVGNINNDKKDE 190

  Fly    76 ------------QARRLLLQ-----------------QSMEYKPYVHAVLALVDG-LPSLSAIYA 110
                        :.||::|.                 :.::...|:.|.|...|| |..:....|
  Rat   191 TYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGA 255

  Fly   111 RIRATQ--DLSHTLIYMSMPTDAYGEEMQATLRFLWRLSVLNVGVVLRPPGDHILMVSYFPFSAL 173
            .:...|  |...:|:                .:|:.|.|.|.   ....||.|...:.|
  Rat   256 NVSGFQIVDYDDSLV----------------SKFIERWSTLE---EKEYPGAHTATIKY------ 295

  Fly   174 HGCQVISANVVNRYQVGTKRWAS---QDYFPSKLGNFYGCLLTCATWEDMPYLVWRPDGSGSFVG 235
                 .||...:..||.|:.:.:   |....|:.||...||..       |.:.|     |..|.
  Rat   296 -----TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLAN-------PAVPW-----GQGVE 343

  Fly   236 IEGALLQFMAENL-------------NFTVGL------------YWM------------------ 257
            ||.||.|...|.|             |:|:.:            ||.
  Rat   344 IERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDT 408

  Fly   258 ----NKEEVLATFDESGRIF-----------DEIFGHHADFSLG-----GFHFKPS-AG------ 295
                ||..|:.|..||..:.           :...|:..|.:..     ||.:|.: .|
  Rat   409 SGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGA 473

  Fly   296 ------------SEIPYSQS-------------------TYYFMS---HIMLVTNLQSAYSAYEK 326
                        .|:.|.::                   :..|||   .||:....:|....:..
  Rat   474 RDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 538

  Fly   327 LSFPFTPLLWRAIGLVLILACLLLMLLVR-----WRHHHEL----------PRNPY--YELLVLT 374
            |. |....:|..|....|...::|.|:.|     | |..|.          ..|.:  :..|..:
  Rat   539 LD-PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW-HTEEFEDGRETQSSESTNEFGIFNSLWFS 601

  Fly   375 MGGNLEDRW--VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQ--- 434
            :|..:....  .|:....|:|...|.|.||::.|.|.:.:...|..:...:|.::..::..|
  Rat   602 LGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEI 666

  Fly   435 -HFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSF-----PALAQQSGSSARVAIL---TPY 490
             :.|:......|. ...|...:..:...|:..:|...|     ..:|:...|..:.|.|   |..
  Rat   667 AYGTLDSGSTKEF-FRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMN 730

  Fly   491 EYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGFLEHWTRQYVSA 555
            ||....:....|.     |...:.::.......:.|.|...:|..:...:..|.|:....::..
  Rat   731 EYIEQRKPCDTMK-----VGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWY- 789

  Fly   556 VDEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLSMRELAALFWLILWANLG-A 619
              :|.|.             |..|    .:|:|       :.:.||:..:|.:|: ||...|| |
  Rat   790 --DKGEC-------------GSGG----GDSKE-------KTSALSLSNVAGVFY-ILVGGLGLA 827

  Fly   620 VVVFVLELLLPRIKLRKILRKMK 642
            ::|.::|..   .|.|...::||
  Rat   828 MLVALIEFC---YKSRAEAKRMK 847

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.