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Protein Alignment Ir7b and Grik1

DIOPT Version :9

Sequence 1:	NP_572410.2	Gene:	Ir7b / 31690	FlyBaseID:	FBgn0029965	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	749	Identity:	135/749 - (18%)
Similarity:	249/749 - (33%)	Gaps:	212/749 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YILSCCSLVASTMESSSDWDLAEALAQVVANSEMGR-----FKT-------LYIYTHTNSQSTGG 58
            |::..||...:          ||.|.|::....|..     |.|       |.:|.::....||.
  Rat   226 YVIFDCSHETA----------AEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGF 280

  Fly    59 HLEELLDQVLMIVPNNLQARRLLLQQSMEY-----KPYVHAVLALVDGLPSLSA--IYARIRATQ 116
            .|..:         :|.....::.:.|||.     :|..    .|:||:.:..|  :|..:....
  Rat   281 RLLNI---------DNPHVSSIIEKWSMERLQAPPRPET----GLLDGMMTTEAALMYDAVYMVA 332

  Fly   117 DLSHTLIYMSMPTDAYGEEMQATLRFLWRLSVLNVGVVLRPPGDHILMVSYFPFSALHGCQV-IS 180
            ..||....:::      ..:|......|||....:.::.....|.  :.....|:...|.:. ..
  Rat   333 IASHRASQLTV------SSLQCHRHKPWRLGPRFMNLIKEARWDG--LTGRITFNKTDGLRKDFD 389

  Fly   181 ANVVNRYQVGTKR------------WASQDYFPSKLG------------NFYGCL----LTCATW 217
            .::::..:.||::            |.....:.|..|            |....|    |...|.
  Rat   390 LDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTI 454

  Fly   218 EDMPYLVWRPD-----GSGSFVGIEGALLQFMAENLNFTV-------GLYWMNKEEVLATFDESG 270
            .:.||:::|..     |:..|.|....||:.::..|.|..       |.|....::     .|..
  Rat   455 LEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDK-----GEWN 514

  Fly   271 RIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMSHIMLVTNLQSAY--------SAYEKL 327
            .:..|:..|.||.::        |...|.|.:......|...:...:...|        ..:..|
  Rat   515 GMVKELIDHRADLAV--------APLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFL 571

  Fly   328 SFPFTPLLWRAIGLVLILACL----LLMLLVR-----WRHHHELPRNPYYELL------------ 371
            : |.:|.:|    :.::||||    :|.::.|     |.:.|  |.||..:::
  Rat   572 N-PLSPDIW----MYVLLACLGVSCVLFVIARFTPYEWYNPH--PCNPDSDVVENNFTLLNSFWF 629

  Fly   372 ----VLTMGGNLEDRWVPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVL 432
                ::..|..|    :|:...:|:|...|.|.||::.|.|.:.:...|..:...:|..:..: |
  Rat   630 GVGALMQQGSEL----MPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADD-L 689

  Fly   433 AQHFTIQLAEVNEARILASLPELR---PEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFG 494
            |:...|:...|.:...:....:.:   .|::.....|..||  ||.:.|....:..:.|.|....
  Rat   690 AKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQS--ALVKNSDEGIQRVLTTDYALLM 752

  Fly   495 YFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVG--------------VLNKQIQHAHTHGFL 545
            ....:..:::|      .....|:...:....:.||              :|..| :....|...
  Rat   753 ESTSIEYVTQR------NCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQ-EEGKLHMMK 810

  Fly   546 EHWTRQYVSAVDEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLSMRELAALFW 610
            |.|.|.                          :|.|     |||.:.|    :.|.:..:..:|
  Rat   811 EKWWRG--------------------------NGCP-----EEDSKEA----SALGVENIGGIF- 839

  Fly   611 LILWANLG-AVVVFVLELLLPRIKLRKILRKMKS 643
            ::|.|.|. :|.|.:.|.|....|...:.:|.||
  Rat   840 IVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKS 873

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.