Protein Alignment Ir7b and Grin2c

DIOPT Version :9

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_036707.3
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 111/654 - (16%)
• Similarity: 211/654 - (32%)
• Gaps: 263/654 - (40%)

  Fly   144 WRLSV-------------------LNVGVVLRPPGD-----------------HILMVSY----F 168
            ||||:                   ...|.:..|.||                 |:|.|::    |
  Rat   294 WRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDF 358

  Fly   169 PFSALHGCQVISANVV----NRYQ----VGTKRWASQDYFPSKLGNFYGCL-------------- 211
            .||.  |..::...:|    ||::    ||  ||.            :|.|
  Rat   359 SFSP--GGYLVRPTMVVIALNRHRLWEMVG--RWD------------HGVLYMKYPVWPRYSTSL 407

  Fly   212 --------LTCATWEDMPY-LVWRPD-GSGSFV----------------------------GIEG 238
                    ||.||.|:.|: :|..|| |:|..|                            |...
  Rat   408 QPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCI 472

  Fly   239 ALLQFMAENLNFTVGLYWMNKEEVLATFDESGR--------IFDEIFGHHADFSLGGFHFKPSAG 295
            .:|:.:|:.:.|:..||       |.|..:.|:        :..|::...||.::|.........
  Rat   473 DILKKLAKVVKFSYDLY-------LVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERS 530

  Fly   296 SEIPYSQSTYYFMSHIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVRWRHHH 360
            ..|.:  |..:..:.|.::.:..:...:......|::|.:|    :::.:.||.::.:..:...:
  Rat   531 EIIDF--SVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVW----VMMFVMCLTVVAITVFMFEY 589

  Fly   361 ELPRNPYYELLV---------LTMGGNLEDRWV-----------PQRFPSRLVLLTWLFATLVLR 405
            ..|.: |.:.|.         .|:|.::...|.           |:...|::::|.|.|..::..
  Rat   590 FSPVS-YNQNLTKGKKPGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFL 653

  Fly   406 SGYQSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQS 470
            :.|.:.:...:.|:...:   |:|.:..:.|.                  ||:          ..
  Rat   654 ASYTANLAAFMIQEQYID---TVSGLSDKKFQ------------------RPQ----------DQ 687

  Fly   471 FPALAQQSGSSARVAILTPYEYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQ 535
            :|                |:. ||    ..|.......:|..        |...|:|:|....:.
  Rat   688 YP----------------PFR-FG----TVPNGSTERNIRSN--------YRDMHTHMVKFNQRS 723

  Fly   536 IQHAHTH---GFLEHW-----TRQYVSAVDE-----------------------KDESVARIAST 569
            ::.|.|.   |.|:.:     ...|::..||                       ||....|....
  Rat   724 VEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDL 788

  Fly   570 SYSTLDGIDGD---------PSLSESEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVVVFVL 625
            :...|.| ||:         ..:.::|:::    |..:.|.:..:|.:|:::|.|...|::||..
  Rat   789 ALLQLLG-DGETQKLETVWLSGICQNEKNE----VMSSKLDIDNMAGVFYMLLVAMGLALLVFAW 848

  Fly   626 ELLL 629
            |.|:
  Rat   849 EHLV 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
Grin2c	NP_036707.3	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	24/118 (20%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	75/474 (16%)
		NMDAR2_C	850..>925	CDD:402274	1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840