Protein Alignment Ir7b and Grin2a

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_036705.3
• Gene: Grin2a / 24409
• RGDID: 2737
• Length: 1464
• Species: Rattus norvegicus
• Alignment Length: 203
• Identity: 29/203 - (14%)
• Similarity: 80/203 - (39%)
• Gaps: 32/203 - (15%)

  Fly   240 LLQFMAENLNFTVGLYWMNKEEVLATFDESGR--------IFDEIFGHHADFSLGGFHFKPSAGS 296
            :|:.::..:.||..||       |.|..:.|:        :..|:....|..::|..........
  Rat   463 ILKKLSRTVKFTYDLY-------LVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSE 520

  Fly   297 EIPYSQSTYYFMSHIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVRW----R 357
            .:.:  |..:..:.|.::.:..:...:......||:..:|..:.::|::...:.:.:..:    .
  Rat   521 VVDF--SVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVG 583

  Fly   358 HHHEL-----PRNPYYEL--LVLTMGGNLEDRWVPQRFP----SRLVLLTWLFATLVLRSGYQSG 411
            ::..|     |..|.:.:  .:..:.|.:.:..||.:.|    |::::..|.|..::..:.|.:.
  Rat   584 YNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTAN 648

  Fly   412 MYQLLRQD 419
            :...:.|:
  Rat   649 LAAFMIQE 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
Grin2a	NP_036705.3	PBP1_iGluR_NMDA_NR2	32..387	CDD:380601
		PBP2_iGluR_NMDA_Nr2	403..802	CDD:270436	29/203 (14%)
		Pore-forming. /evidence=ECO:0000250|UniProtKB:B7ZSK1	599..620		3/20 (15%)
		NMDAR2_C	839..1464	CDD:463148
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	989..1083
		PDZ-binding. /evidence=ECO:0000305	1462..1464