Protein Alignment Ir7b and grin3b

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 809
• Identity: 136/809 - (16%)
• Similarity: 250/809 - (30%)
• Gaps: 287/809 - (35%)

  Fly    16 STMESSS----------DWDLAEALAQVVANSEMGRFKTLYIYTHTNSQSTGGHLEELLDQVLMI 70
            |.:::||          .||.|.....:.:|:      ||...|                 :|.|
 Frog   164 SVLQNSSWEEVDIITCHPWDSASIQRYLTSNT------TLVSRT-----------------ILNI 205

  Fly    71 VPNNLQARRLLLQQSME--YKPYVHAVLALVDGLPSLSAIYARIRATQD-----------LSHTL 122
            .|.:..|....|||..|  ..|....:|...|...| |.::   |..:|           :.|.|
 Frog   206 HPVDESALVPFLQQHFESMKNPQFPMLLYGCDARRS-SLVF---RVARDCGLEAHEFHWMIGHPL 266

  Fly   123 IYMSMPTD-------AYGEEMQATLRFLWRLSV------LNVGVVLRP----------------- 157
            ....|.|:       ||||..:.|:....|.:|      ::..|.:||
 Frog   267 NGEEMTTEGMPPGLLAYGEVSRPTMEKFIRDAVGLVTRAISAAVHVRPDLALIQSMVNCNDKQTK 331

  Fly   158 ----PGDHI-LMVSYFPFSALHGCQVISANVVN-----------RYQVGTKRWAS---------- 196
                .|.:: ..::...||...|...:|.|:::           |..:|...|.:
 Frog   332 QNESSGSYLSRFLANTSFSGQTGQIYVSNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQGKME 396

  Fly   197 ----------QDYFPSKLGNFYGCLLTCATWEDMPYLVWR------------------------- 226
                      |.:.|:. |.|....|...|..:.|::..|
 Frog   397 VEEGLWQSRIQQWEPAP-GGFARTKLRVVTLVEHPFVFTREVDADGSCPAGQMCLDPRTNNSAVL 460

  Fly   227 ---------PDGSGSFVGIEGA---------LLQFMAENLNFTVGLYWMNKEEVLATFDESGRIF 273
                     |:||   |.:|..         ||:.::|:|.|...||      ::.......|..
 Frog   461 DVLFEELNSPNGS---VPLEYKTCCYGYCIDLLEKLSEDLRFDFELY------IVGDGKYGARKG 516

  Fly   274 DEIFGHHADFSLGGFHFKPSAGSEIPYSQSTY------YFMSHIMLVTNLQSAYSAYEKLSFPFT 332
            |...|...|...|..|...::.| |..::||.      ::.:.:.::..::...|......:|..
 Frog   517 DRWTGLVGDLLSGAAHMAVTSFS-INSARSTVIDFTSPFYSTSLGILVRMRDTASPIGAFMWPLH 580

  Fly   333 PLLWRAIGLVLILACLLLMLLVRWRH-----HHELPRNPYY------ELLVLTMGGNLEDRWVPQ 386
            ..:|..|.:.|.:..|.| ....|:.     .|...|...:      .|....:.|.......|:
 Frog   581 WSMWVGIFVALHITALFL-TFYEWKSPFGMTPHGRNRTKIFSYSSALNLCYAILFGRTVSSKTPK 644

  Fly   387 RFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNEARILAS 451
            ....|:::..|....|::.|.|.:.:..::..|      :|. |.|:.....:|...::.....:
 Frog   645 CCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGD------KTF-EALSGIHDPKLHHPSQGFRFGT 702

  Fly   452 LPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFGYFRK--VHPMSRRLHLVRE--- 511
            :.|...||  |::    :|||                  |...|.||  |...|..:||::.
 Frog   703 VWESSAEQ--YIK----KSFP------------------EMHNYMRKFSVPATSDGVHLLKTDPP 743

  Fly   512 ----------------------RIYTQQLAFYVR-------RHSHLVGVLNKQIQHAHTHGFLEH 547
                                  ::.|....|.:.       ::|.|...:::.|....:.||::
 Frog   744 TLNAFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMD- 807

  Fly   548 WTRQYVSAVDEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLSMRELAALFWLI 612
                   .:.:|...:.......|:..:.:.                     :.:...:.||.|:
 Frog   808 -------TLHDKWYKMVPCGKRVYAVTETLQ---------------------MGIYHFSGLFVLL 844

  Fly   613 LWANLGAVVVFVLE-----LLLPRIKLRK 636
            .....|:::..::|     |:||||:.|:
 Frog   845 CIGFCGSLLTSLMERVVYHLILPRIRRRR 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	48/264 (18%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	72/445 (16%)
		Lig_chan	580..847	CDD:459656	48/327 (15%)