Protein Alignment Ir7b and grik4

DIOPT Version :10

• Sequence 1: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_031761990.1
• Gene: grik4 / 100490768
• XenbaseID: XB-GENE-1011875
• Length: 962
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 129/682 - (18%)
• Similarity: 236/682 - (34%)
• Gaps: 171/682 - (25%)

  Fly    37 SEMGRFKTLYIYTHTNSQSTGGHLEELLDQVLMIVPNNL--QARRLL------LQQSME----YK 89
            :|:|.....|.|..||.:......|..||..:.|:..::  |:....      ||||.|    :.
 Frog   231 AELGMVTAYYTYIFTNLEFVLQRFESPLDDRVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDHS 295

  Fly    90 PYVHAVL--ALVDGLPSLSAIYARIRATQDLSHTLIYMSMPTDA-------YGEEMQATLRFLWR 145
            |:....|  ||:     ..|:|..:.|.|:|:.:......|...       :|..:...||.: .
 Frog   296 PFTGPALSAALL-----FDAVYGIVSAVQELNRSQEIGVKPLSCGSSQIWQHGTSLMNYLRMV-E 354

  Fly   146 LSVLNVGVVLRPPGDH------ILMVSYFPFSALHGCQVISA-NVVNRYQVGTKRWASQDYFPSK 203
            |..|...|.....|..      |:..:...|..:....|.:. |:..||           :.|:.
 Frog   355 LEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTNGLNMDKRY-----------FSPNA 408

  Fly   204 LGNFYGCLLTCAT----WEDMPYLVWRP-----DGSGSFVGIEGALLQFMAENLNFTV------- 252
            ........|...|    .::.|||:.:.     :|:..:.|....:|:.:|..|.|..
 Frog   409 SDTLVNKTLIVTTILFFLQENPYLMLKANHQELEGNDRYEGFCVDMLKELAAILRFNYKIRLVAD 473

  Fly   253 GLYWMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMSHIMLVTNL 317
            |:|.:  .|:..|:  :|.: .|:....||.::.|..........|.:|:.   ||:  :.::.|
 Frog   474 GVYGV--PELNGTW--TGMV-GELISRKADLAVAGLTITAEREKVIDFSKP---FMT--LGISIL 528

  Fly   318 QSAY----SAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVR-----WRHHHELPRNPYYELLV- 372
            ...:    ..|.....||:|.:|..:.|..:....:|.|:.|     |...|...:. ...|||
 Frog   529 YRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQG-RCNLLVN 592

  Fly   373 -LTMGGNLEDRW-------------VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRN 423
             .::|.:|   |             .|:...:|.|...|...||::.|.|.:.:...|.......
 Frog   593 QYSLGNSL---WFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDV 654

  Fly   424 PPQTISEVLAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILT 488
            |.:::.: ||...||:...::..           ..:.:.:.|..|::..:
 Frog   655 PIESVDD-LADQTTIEYGTIHGG-----------SSMTFFQNSRYQTYQRM-------------- 693

  Fly   489 PYEYFGYFRKVHPMSRRLHLVRE---RIYTQQLAF---------YVRRHSHLVGVLNKQIQHAHT 541
                :.|.....| |..:....|   |:.....||         |.:|:.:|..|
 Frog   694 ----WNYMHSKQP-SVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQV---------- 743

  Fly   542 HGFLEHWTRQYVSAV-------DEKDESVARIASTSYSTLDGID---GDPSLSESEEDQQVAPVR 596
            .|.|:  |:.|...:       ||.|.::.::...  :.|:.:.   .|......|||.     |
 Frog   744 GGLLD--TKGYGIGMPVGSAFRDEFDLAILQLQEN--NCLEDLKRKWWDGGKCPKEEDH-----R 799

  Fly   597 QNVLSMRELAALFWLILWANLGAVVVFVLELL 628
            ...|.|..:..:|.:::...:.|:::.:||.|
 Frog   800 AKGLGMENIGGIFVVLICGLIVAILIAMLEFL 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7b	NP_572410.2	None
grik4	XP_031761990.1	Periplasmic_Binding_Protein_type1	23..400	CDD:471960	37/174 (21%)
		PBP2_iGluR_kainate_KA1	414..788	CDD:270442	77/432 (18%)