Protein Alignment CARPA and CA12

DIOPT Version :10

• Sequence 1: NP_572407.3
• Gene: CARPA / 31687
• FlyBaseID: FBgn0029962
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001209.1
• Gene: CA12 / 771
• HGNCID: 1371
• Length: 354
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 83/268 - (30%)
• Similarity: 131/268 - (48%)
• Gaps: 19/268 - (7%)

  Fly    39 WTYDGISGPSFWGLINPQWNMCNKGRRQSPIDVVPDKLLFDPYLRPLHIDKHKVSGT----LHNT 99
            |||.|..|.:.|   :.::..|. |..|||||:..|.|.:|..|.||....:.:|..    |.|.
Human    32 WTYFGPDGENSW---SKKYPSCG-GLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNN 92

  Fly   100 GQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTEN-VRGSEHFIQGYSFPGEIQIYGFNK 163
            |.|:...:..|    ::|.|  |..||...::::|:|..| ..||||.:.|..|..|:.|..:|.
Human    93 GHSVKLNLPSD----MHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNS 151

  Fly   164 ELYHNMSEAQHKSQGIVGLSLMVQIGETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLP-NT 227
            :||.:.|.|.:||:|:..|::::::|.. ||....|.|....|.|:|....:...::..||| .|
Human   152 DLYPDASTASNKSEGLAVLAVLIEMGSF-NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERT 215

  Fly   228 DHYITYEGSTTHPGCWESTVWIIVNKPIYITKQELYQLRRLMQGSESTPKAP--LGNNARPVQSL 290
            ..|..|.||.|.|.|..:.:|.:...|:.|::::|..|...:..:.....:|  :.||.|.||..
Human   216 AEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKF 280

  Fly   291 HHRTVRTN 298
            ..|.|.|:
Human   281 DERLVYTS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CARPA	NP_572407.3	alpha_CARP_X_XI_like	46..300	CDD:239395	79/261 (30%)
CA12	NP_001209.1	alpha_CA_XII_XIV	39..289	CDD:239400	79/261 (30%)