DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CARPA and ca9

DIOPT Version :9

Sequence 1:	NP_001284986.1	Gene:	CARPA / 31687	FlyBaseID:	FBgn0029962	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_009303384.1	Gene:	ca9 / 566612	ZFINID:	ZDB-GENE-080818-5	Length:	384	Species:	Danio rerio

Alignment Length:	341	Identity:	94/341 - (27%)
Similarity:	151/341 - (44%)	Gaps:	40/341 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GFIACSAIVLL------CSSEVLSSWEEWWTYDGISGPSFWGLINPQ-W----NMCNKGRRQSPI 69
            ||:....:.||      .|.|..||..:.....|.|....||..:.. |    ..|. |:.||||
Zfish     4 GFLLILHLQLLLVASSSSSEEDKSSERDGQHSKGSSHQHHWGYQDQDAWLSAFEHCG-GKSQSPI 67

  Fly    70 DVVPDKLLFDPYLRPLHIDKHKVSG----TLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEE 130
            ::...|:|.:|.|.|:.:|.:.::|    ||.|.|.:|...:...           :..|..|::
Zfish    68 NIDTHKVLHEPRLPPIQLDGYDLTGSHSLTLLNNGHTLQLSLPSS-----------MRIRRGFDQ 121

  Fly   131 IYI------HYGTENVRGSEHFIQGYSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQIG 189
            :|:      |:||..|.||||.|....:|.||.:..:|.: |.|::||..|:.|:..|...:.||
Zfish   122 VYVAAQLHFHWGTTEVPGSEHTIDNIHYPAEIHVVHYNSK-YANLTEAASKADGLAVLGGFIAIG 185

  Fly   190 ETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLPNT-DHYITYEGSTTHPGCWESTVWIIVNK 253
            ...|.....|.|..:.|......|.|...:||.||||: :.:..|.||.|.|.|.::..|.:.|.
Zfish   186 LHENDNYEKILSALSDVSTEESLTVIPGFNVRHLLPNSLERFYRYSGSLTTPPCLQTVSWTLFND 250

  Fly   254 PIYITKQELYQLRRLMQGSESTPKAPLGNNARPVQSLHHRTVRTNIDFK-RNKNQYACPSMYKDM 317
            .|.::::   ||..|.:..::.....|..|.|..|.||.|.::::.... ..|.:.|.|:..:|.
Zfish   251 SIRVSRR---QLAALEESLKTEHNKLLSKNFRAPQLLHGRKIQSSFHTSDSGKTRGATPTETQDK 312

  Fly   318 YYRANRWSPD-TGLLI 332
            ..:.:...|. ||.::
Zfish   313 NIKESSAHPSLTGHIL 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CARPA	NP_001284986.1	alpha_CARP_X_XI_like	46..300	CDD:239395	77/269 (29%)
ca9	XP_009303384.1	alpha_CA_IX	48..294	CDD:239403	75/261 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920