back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CARPA and CA13

DIOPT Version :9

Sequence 1:	NP_001284986.1	Gene:	CARPA / 31687	FlyBaseID:	FBgn0029962	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_940986.1	Gene:	CA13 / 377677	HGNCID:	14914	Length:	262	Species:	Homo sapiens

Alignment Length:	263	Identity:	93/263 - (35%)
Similarity:	142/263 - (53%)	Gaps:	11/263 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 WTYDGISGPSFWGLINPQWNMCNKGRRQSPIDVVPDKLLFDPYLRPLHIDKHKVSGT--LHNTGQ 101
            |.|...:||..|....|    ...|.:||||::...::.:|..||||.| |:..|..  :.|:|.
Human     6 WGYREHNGPIHWKEFFP----IADGDQQSPIEIKTKEVKYDSSLRPLSI-KYDPSSAKIISNSGH 65

  Fly   102 SLVFRVD-KDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQGYSFPGEIQIYGFNKEL 165
            |  |.|| .||:....:.||||...|:..::::|:|:.:..||||.:.|.|:..|:.:..:|.:.
Human    66 S--FNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDK 128

  Fly   166 YHNMSEAQHKSQGIVGLSLMVQIGETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLPNTDHY 230
            |.:..||.|:..|:..|.:.:|||| ||.:|:.||.|.:.:..:|..|...:..:.||||.:..|
Human   129 YPSFVEAAHEPDGLAVLGVFLQIGE-PNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDY 192

  Fly   231 ITYEGSTTHPGCWESTVWIIVNKPIYITKQELYQLRRLMQGSESTPKAPLGNNARPVQSLHHRTV 295
            .||.||.|.|...||..||::.:||.|:.|:|.:.|.|:..:|....|.|.:|.||.|.|..|.|
Human   193 WTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKV 257

  Fly   296 RTN 298
            |.:
Human   258 RAS 260

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.