DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7a and grid1a

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_021323097.1	Gene:	grid1a / 793756	ZFINID:	ZDB-GENE-120411-28	Length:	1044	Species:	Danio rerio

Alignment Length:	484	Identity:	96/484 - (19%)
Similarity:	164/484 - (33%)	Gaps:	98/484 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 RLLNMDCDLSVNLELIDIYKNGLFRHGHEARSFNRVLSLSGCPLQVSWYPLPPFVSFIGN-SSDP 238
            ||...|.|..:|..|    :.....||           :.|..|:|......|||....| ...|
Zfish   412 RLATWDSDRGLNGSL----RENRADHG-----------MQGITLKVVTLLEEPFVMVAENILGQP 461

  Fly   239 EERAQIWRLTGIDGELIKLLASIFDFRILLEEPCN-KCLSPDIKDDCSGCFDQVIISNSSILIGA 302
            :      |..|...:::..||.|..|:..:.:..: |..||......:|...::|...:.:.|.|
Zfish   462 K------RYKGFSIDVLDALAKILGFKYEMYQVADAKYGSPQTNGSWNGMIGELIGKRADVAISA 520

  Fly   303 MSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAVPFTVIVWLALVVSSLLLVLVLWMRN 367
            ::.:.:..:...|:..|...|:..:|..:.:...:..|..||.:.||..:..:..::.:::::..
Zfish   521 ITITPERENVVDFSKRYLDYSVGILMTKTEERLNIFSLLAPFDLAVWACIAAAIPVVGVMVFLLR 585

  Fly   368 RLVCGRSD--LASHALQVLTTLMGNPL----------EARSLPRSSRLRILYAGWLLLVLVLRVV 420
            |:...||.  ...|....:||...:.:          ...|...|..|||....|.|..|::...
Zfish   586 RVQSVRSQNPPGPHQPASVTTSFQSAIWIVYGAFVQQGGESFMSSMALRIAMGSWWLFTLIVCSS 650

  Fly   421 YQGKLFDSFRLPYHKPLPTEISELIRSNYTLINQEYLDY-YPRELTVLTRNGSKDRFDYIQGLGK 484
            |...|.....:       :.:...||:...|..|..::| ..||..|         |:|.:..|.
Zfish   651 YTANLAAYLTV-------SRMDNAIRTFQDLSKQSEINYGTVRESAV---------FEYFRVKGT 699

  Fly   485 ---EGKFTTTSLIATMEYYNMMHWSTSRLTHIKEHI---------FLYQMVIY------------ 525
               |...|...|..|:   |......:.:|...|.|         ||:.|.:.
Zfish   700 NPLEQDSTFAELWRTI---NKNQGQDNSVTSPAEGIRKVKRDPYAFLWDMAVLEYAALTDDDCTL 761

  Fly   526 ---------------LRRHSLLKFAFDRKIKQLLSAGIIGYFVREF----DACQYRKPFEEDYEV 571
                           |:..|..:..|.:||..|...|.:....:::    ..|...|..|...|.
Zfish   762 VVTGNGMSSKGYGLALQHGSPYRDLFSQKILDLQEKGDLDILKQKWWPRKGRCDLDKHAEPQTEG 826

  Fly   572 TPIPLDSFCGLYYISLIWLSAAVVAFILE 600
            ..:.|.||.|::.|....|..|.:...||
Zfish   827 RALRLHSFAGVFCILAAGLLLACLVAALE 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
grid1a	XP_021323097.1	Periplasmic_Binding_Protein_Type_1	25..424	CDD:324556	4/11 (36%)
		PBP2_iGluR_delta_1	437..809	CDD:270448	75/396 (19%)
		DNA_pol3_gamma3	<915..1044	CDD:331207
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810