DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7a and grid1b

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_009304811.1	Gene:	grid1b / 557511	ZFINID:	ZDB-GENE-121214-84	Length:	1048	Species:	Danio rerio

Alignment Length:	467	Identity:	85/467 - (18%)
Similarity:	159/467 - (34%)	Gaps:	95/467 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 HG-----HEARSFNRVLSLSGCPLQVSWYPLPPFVSFIGN-SSDPEERAQIWRLTGIDGELIKLL 258
            ||     .|:|..|   .:.|..::|......|||....| ...|:      |..|...::::.|
Zfish   420 HGLNGSLKESRIEN---GMQGVTVKVVTLLEDPFVMVAENILGQPK------RYKGFSIDVLEAL 475

  Fly   259 ASIFDFRILLEEPCNKCLSPDIKD-DCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQS 322
            |.|..|:..:.:..:......:.: ..:|...::|...:.:.:.|::.:.:..:...|:..|...
Zfish   476 AKILGFKYDIYQVADSKYGSQLSNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDY 540

  Fly   323 SLVFIMHMSSQFGAVAQLAVPFTVIVWLALVVSSLLLVLVLWMRNRLVCGRSDL---ASHALQVL 384
            |:..:.....:...:..|..||.:.||..:..:..::.:::::..|:...||..   |.||
Zfish   541 SVGILHRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHA---- 601

  Fly   385 TTLMGNPLEAR--------------SLPRSSRLRILYAGWLLLVLVLRVVYQGKLFDSFRLPYHK 435
             :.|.|.|.:.              |:..|..|||:...|.|..|::...|...|.....:
Zfish   602 -SSMSNSLHSAIWIVYGAFVQQGGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAAFLTV---- 661

  Fly   436 PLPTEISELIRSNYTLINQEYLDY-YPRELTVLTRNGSKDRFDYIQGLGK---EGKFTTTSLIAT 496
               :.:...||:...|..|....| ..|:..|         :||.:..|.   |...|...|..|
Zfish   662 ---SRMDNTIRTFQDLARQMDFAYGTVRDSAV---------YDYFKAKGTNPLEQDSTYAELWRT 714

  Fly   497 MEYYNMMHWSTS------RLTHIKEHIFLYQMV---------------------------IYLRR 528
            :...|...:|.|      |......:.||:.|.                           |.::.
Zfish   715 ISKNNGQDFSVSSPSEGIRKAKKGPYAFLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQH 779

  Fly   529 HSLLKFAFDRKIKQLLSAGIIGYFVREF----DACQYRKPFEEDYEVTPIPLDSFCGLYYISLIW 589
            .|..:....:||.:|...|.:....:::    ..|..........:...:.|.||.|::.|....
Zfish   780 GSPYRDLISQKILELQEKGDLDVLKQKWWPRTGRCDLNSHSNAQPDGRSLKLHSFAGVFCILAAG 844

  Fly   590 LSAAVVAFILEL 601
            |..|.:...||:
Zfish   845 LLLACLVAALEM 856

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
grid1b	XP_009304811.1	PBP1_iGluR_delta_1	25..424	CDD:107387	2/3 (67%)
		ANF_receptor	36..400	CDD:279440
		Periplasmic_Binding_Protein_Type_2	437..809	CDD:304360	70/398 (18%)
		Lig_chan	565..840	CDD:278489	53/295 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810