DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir7a and Ekar

DIOPT Version :9

Sequence 1:NP_572406.1 Gene:Ir7a / 31686 FlyBaseID:FBgn0029961 Length:614 Species:Drosophila melanogaster
Sequence 2:NP_001036250.1 Gene:Ekar / 43806 FlyBaseID:FBgn0039916 Length:899 Species:Drosophila melanogaster


Alignment Length:645 Identity:102/645 - (15%)
Similarity:220/645 - (34%) Gaps:198/645 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   105 QAFNTLGFHFT---------DIHSTREFNFLILLTHRMSSRAE--RLQVLRDI--------SRTC 150
            |..|...:|:.         |:...: :||:.:.:.|:...|:  ..|:|:||        .:..
  Fly   217 QQMNEYKYHYLFTSFDLETYDLEDFK-YNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPY 280

  Fly   151 VRFHTSNVILLTEKRDGVVL--VYAY-------------RLLNMDCD------------------ 182
            :..|.....:| |....::.  ||.:             .|||:.|:                  
  Fly   281 LNLHIKKSTIL-ESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAV 344

  Fly   183 ----------------LSVNLELIDIYKNGLFR------HGH----------EARSFN---RVLS 212
                            :...|:||.:.::.:.:      |||          :|.|.|   .|::
  Fly   345 EWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVTLVVIT 409

  Fly   213 LSGCPLQVSWYPLPPFVSFIGNSSDPEERAQIWRLTGIDGELIKLLASIFDFRILLEEPCNKCLS 277
            :...|..:..|.    .:|.||.          |..|...::::.::....|..:|:      |.
  Fly   410 ILETPYVMMHYG----KNFTGNE----------RFYGFCVDILETISREVGFDYILD------LV 454

  Fly   278 PDIK--------DDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHM-SSQ 333
            ||.|        .:.:|...|::...:.:.:|:|:.::...|...||..:....:..:..: :|:
  Fly   455 PDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSE 519

  Fly   334 FGAVAQLAVPFTVIVWLALVVSSLLLVLVLWMRNRL---------VCGRSDLA---------SHA 380
            ...:.....|..:.:|:.::::..|:.|.:::..:|         .|...:::         |..
  Fly   520 PTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFW 584

  Fly   381 LQVLTTLMGNPLEARSLPRSSRLRILYAGWLLLVLVLRVVYQGKLFDSFRLPYHKPLPTEISELI 445
            ..:.|.:..:|   ...||:...||:.:.|....|::...|...| .:|........|.|.:|.:
  Fly   585 FTIGTFMQQSP---DIYPRAMSTRIISSTWGFFSLIIVASYTANL-AAFLTTERMINPIENAEDL 645

  Fly   446 R-------------SNYTLINQEYLDYY-----------PRELTVLTRNGSK------------- 473
            .             |..|......::.|           |...|....:|.|             
  Fly   646 ASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMES 710

  Fly   474 DRFDYIQGLGKEGKFTTTSLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDR 538
            ...|||  :.::...|....:...:.|.:   :|.:.:..::.|.|  .::.|:....::..:|:
  Fly   711 TMLDYI--VQRDCNLTQIGGLLDTKGYGI---ATPKGSPWRDKISL--AILELQERGDIQMLYDK 768

  Fly   539 KIKQLLSAGIIGYFVREFDACQYRKPFEEDYEVTPIPLDSFCGLYYISLIW-LSAAVVAF 597
                        ::....:.|. ||...:..:...:.|:|..|::.:.:.. :.||||||
  Fly   769 ------------WWKNTDETCT-RKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAF 815

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7aNP_572406.1 None
EkarNP_001036250.1 PBP1_iGluR_Kainate 24..388 CDD:107377 27/172 (16%)
ANF_receptor 39..371 CDD:279440 24/155 (15%)
PBP2_iGluR_Kainate 402..771 CDD:270432 61/411 (15%)
Lig_chan 533..807 CDD:278489 43/297 (14%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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