Protein Alignment Ir7a and gria4b

DIOPT Version :9

• Sequence 1: NP_572406.1
• Gene: Ir7a / 31686
• FlyBaseID: FBgn0029961
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 692
• Identity: 119/692 - (17%)
• Similarity: 230/692 - (33%)
• Gaps: 170/692 - (24%)

  Fly    33 AALEILAEQVSPSQSTLAVMDLTQDAEHRDERQEQLMTI---------ILRSVG-SEMALRTFQK 87
            |:...|.|.:...|....|:||  :||..:...||::::         |:.::| .::.|..|..
Zfish   192 ASYRQLLEDLDRRQEKTFVIDL--EAERLNNMLEQIVSVGKHVKGYHYIMANLGFKDINLERFMH 254

  Fly    88 PPAEVPASFVV-----FLVNSAQAFNTLGFHFTDIHSTREF-------NFLILLTH-RMSSRAER 139
            ..|.|....:|     .::...|.:|.|        ..||:       .:...||: .:...||.
Zfish   255 GGANVTGFQLVDFSNPMVIKLMQRWNKL--------DQREYPGSDAPPKYTSALTYDGVMVMAEA 311

  Fly   140 LQVLR----DISRTCVRFHTSNVILLTEKRDGVVLVYAYRLLNMDCDLSVNLELIDIY-KNGLFR 199
            .:.||    ||||..:.              |..|.......|...|:...|:.:.:. ..|..:
Zfish   312 FRNLRRQKVDISRRGIA--------------GDCLANPAAPWNQGIDMERTLKQVHLQGLTGNVQ 362

  Fly   200 HGHEARSFNRVLSL----SGCPLQVSWYP-------------LPPFVSFIGNSSDPEERAQI--- 244
            ..|..|..|..:.:    |..|.::.::.             ||      ..:|..|.|..|
Zfish   363 FDHYGRRVNYTMDVFELKSNGPRRIGYWNDADKLVLTQDHALLP------NETSGMENRTVIVTT 421

  Fly   245 ------------WRL----TGIDGELIKLLASI-----FDFRILLEEPCNK--CLSPDIKDDCSG 286
                        |.:    ...:|..:.|.:.|     |.::|.: .|..|  ...|:.| ..:|
Zfish   422 IMEGPYVMLKKNWEMYEGNEQYEGYCVDLASEIAKHIGFKYKISI-VPDGKYGARDPETK-IWNG 484

  Fly   287 CFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSL-VFIMHMSSQFGAVAQLAVPFTVIVWL 350
            ...:::...:.|.:..::.:........|:..:....: :.|.........|.....|....:|:
Zfish   485 MVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 549

  Fly   351 ALVVSSLLLVLVLWMRNRLVCGRSDLASHALQVLTTLMGNPLEA--------RSL---------- 397
            .:|.:.:.:.:||::.:|.    |....|..:......|.|.:.        .||
Zfish   550 CIVFAYIGVSVVLFLVSRF----SPYEWHTEEPEEGTDGLPSDQPPNEFGIFNSLWFSLGAFMQQ 610

  Fly   398 -----PRSSRLRILYAGWLLLVLVLRVVYQGKLFDSFRLPYHKPLPTEISELIRSNY-----TLI 452
                 |||...||:...|....|::...|...| .:|........|.|.:|.:....     ||.
Zfish   611 GCDISPRSLSGRIVGGVWWFFTLIIISSYTANL-AAFLTVERMVSPIESAEDLAKQTDIAYGTLD 674

  Fly   453 NQEYLDYYPR----------------ELTVLTRNGSKDRFDYIQGLGK----EGKFTTTSLIATM 497
            :....:::.|                |.||.|:..:       :|:.:    :||:... |.:||
Zfish   675 SGSTKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTA-------EGVARVRKSKGKYAFL-LESTM 731

  Fly   498 EYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREF----DA 558
            ..|.........: .:..::......:...:.|.|:.|.:..:.:|...|::.....::    ..
Zfish   732 NEYTEQRKPCDTM-KVGGNLDSKGYGVATPKGSQLRSAVNLAVLKLNEQGLLDKLKNKWWYDKGE 795

  Fly   559 CQYRKPFEEDYEVTPIPLDSFCGLYYISLIWLSAAVVAFILE 600
            |......|:|.....:.|.:..|::||.:..|..|::..::|
Zfish   796 CGSGGGGEKDKSSQALSLSNVAGVFYILVGGLGLAMLVALIE 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	44/229 (19%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	61/394 (15%)
		Lig_chan	546..827	CDD:306551	50/294 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810