DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7a and Ir21a

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	107/577 - (18%)
Similarity:	208/577 - (36%)	Gaps:	112/577 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 SFVVFLVNSAQAFNTLGFHFTDIHSTREFNFLILLTHRMSSRAERLQVLRDISRTCVRFHTSNVI 159
            |:::||.:.......||        .:..:.::|::.....|      |||...:.:..:..|::
  Fly   167 SYILFLSDPLMTRKILG--------PQTESRVVLVSRSTQWR------LRDFLSSELSSNIVNLL 217

  Fly   160 LLTEK------RDGVVLVYAYRLLNMDCDLSVNLELIDIYKNGLFRHGHEARSFNRVLSLSGCPL 218
            ::.|.      |:...::|.::|.......:..:.|....|..|.|..............:|...
  Fly   218 VIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRF 282

  Fly   219 QVSWYPLPPFVSFIGNSSDPEERAQIWRLTGIDGELIKLLASIFDFRILLEEPCNKCLSPDIKDD 283
            |:|....|||: |...:.|.....|: |..|::..|:.:::...:|.|.:.|...:..:..:.|.
  Fly   283 QISAANQPPFI-FRIRTLDSSGMGQL-RWDGVEFRLLTMISKRLNFSIDITETPTRSNTRGVVDT 345

  Fly   284 CSGCFDQVIISNSSILIGAMSGSH--QHRSHFSFTSSYHQ-SSLVFIMHMSSQFGAVAQLAVPFT 345
            ..   :|:|  ..::.|| |||.:  |.|...|..|..|. ....||...|........:..||.
  Fly   346 IQ---EQII--ERTVDIG-MSGIYITQERLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQ 404

  Fly   346 VIVWLALVVSSLLLVLVLWMRNRLVCGRSDLASHALQVLTTLMGNPLEARSL------------- 397
            ..||:||:...|..:..:...:||             .|:.||||..|..::
  Fly   405 WPVWVALICVYLGGIFPIVFTDRL-------------TLSHLMGNWGEVENMFWYVFGMFTNAFS 456

  Fly   398 ---------PRSSRLRILYAGWLLLVLVLRVVYQGKLFDSFRLPYHKPLPTEISELIRSNY---T 450
                     .|.:..|:|...:.|..:::...|.|.:.....||........:.:|:...:   |
  Fly   457 FTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLFFRVGT 521

  Fly   451 LINQEYLDYYPRELTVLTRN--------GSKDRFDYIQGLGK--EGKFTTTSLI---ATMEYYNM 502
            |.|..:..::.....:.|..        ||.|     :|:|.  :..|...:.:   |.:||...
  Fly   522 LNNGGWETWFQNSTHIPTSRLYKKMEFVGSVD-----EGIGNVTQSFFWNYAFLGSKAQLEYLVQ 581

  Fly   503 MHWSTSRLT-----HIKEHIF-LYQMVIYLRRHSLLKFAFDRKIKQLLSAGII------------ 549
            .::|...::     |:.|..| |:|:.....|.|:.|...|..|.....:|:|
  Fly   582 SNFSDENISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQ 646

  Fly   550 ----GYFVREFDACQYRKPFEEDYEVTPIPLDSFCGLYYISLIWLSAAVVAFILELL 602
                |..::...:...|:..:|:.::|....:   |::.:..:.......|.:.|::
  Fly   647 RSSSGRLLQASSSNSLREIIQEERQLTTADTE---GMFLLMALGYFLGATALVSEIV 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	65/319 (20%)
Ir21a	NP_001097043.1	Lig_chan	407..662	CDD:278489	49/272 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810