Protein Alignment Ir7a and Nmdar2

DIOPT Version :9

• Sequence 1: NP_572406.1
• Gene: Ir7a / 31686
• FlyBaseID: FBgn0029961
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 116/760 - (15%)
• Similarity: 242/760 - (31%)
• Gaps: 242/760 - (31%)

  Fly    45 SQSTLAVMDLTQDAEHRD-------ERQE--QLMTIILRSVGSEMALRTFQKPPAEVPASFVVFL 100
            |||||. :.|....||:.       ||.:  |...:..:..|.:..::..::..||:...|...:
  Fly   224 SQSTLQ-LQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTI 287

  Fly   101 VNSAQAFNTLGFHFTDIHSTREFNFLILLTHRMSSRAERLQVLR--------------------- 144
            :||.....|     :|:.........::|.:  :::.|.:.:||
  Fly   288 LNSIVVTRT-----SDLMELVNSEARVMLLY--ATQTEAITILRAAEEMKLTGENYVWVVSQSVI 345

  Fly   145 ---------DISRTCVRFHTSNVILLTEKRDGVVLVYAYRL-------LNMDCDLSVNLELIDIY 193
                     .:....|.|.||:..|:.| ....:.:|:|.:       .|.|..|:......:..
  Fly   346 EKKDAHSQFPVGMLGVHFDTSSAALMNE-ISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDE 409

  Fly   194 KNGLFRHGHEARSFNRVLSLSG-----------------CPLQVS------------WYPLPPF- 228
            ..|.:.:|.....:.|.:|:.|                 ..|::.            |..:..:
  Fly   410 GRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWK 474

  Fly   229 -----------VSFIGNSSDPE--------------ERAQIWRLTGIDGELIKLLASIFDFRILL 268
                       :::.|||..|.              |.|....|:..|....|.|   .|..:|.
  Fly   475 SWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCL---MDRGVLC 536

  Fly   269 EEPCNKCLSPDIK-----------DDCSG-CFD-------------------------------- 289
            ....:..::.||.           ..||| |.|
  Fly   537 RVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWN 601

  Fly   290 ----QVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAV--PFTVIV 348
                .::...:.:::.::..:.:..:...|:..:.::.:..:  ::.:.|.::..|.  ||....
  Fly   602 GLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIV--VAKRTGIISPTAFLEPFDTAS 664

  Fly   349 WL-----ALVVSSLLLVLVLWMR-----NRLVCGRSDLASHALQVLTT-------LMGNPLEARS 396
            |:     |:..::.::.|..|:.     .:|....:::..:...:..|       |....:...|
  Fly   665 WMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDS 729

  Fly   397 LPRSSRLRILYAGWLLLVLVLRVVYQGKL---------FDSF------RL--PY-HKP------L 437
             ||....|.:...|.|..:|...:|...|         |..|      ||  |: |||      :
  Fly   730 -PRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTI 793

  Fly   438 PTEISELIRSNYTLINQEYLDYYPR----ELTVLTRNGSKDRF-------DYIQGLGKEGKFTTT 491
            |...::.....|..:...|:..|.:    :......||:.|.|       ||:....::.:..|.
  Fly   794 PYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTV 858

  Fly   492 SLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREF 556
            .....|..|.:.....|:             .:.:....||:|..:..:::|....:.|
  Fly   859 GSWYAMTGYGLAFSRNSK-------------YVQMFNKRLLEFRANGDLERLRRYWMTG------ 904

  Fly   557 DACQYRKPFEEDYEVT-PIPLDSFCGLYYISLIWLSAAVVAFILE 600
             .|   :|.:::::.: |:.|:.|...:.:.:..:..|.:..:||
  Fly   905 -TC---RPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLE 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	41/274 (15%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	64/434 (15%)
		Lig_chan	665..928	CDD:278489	48/286 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900