Protein Alignment Ir7a and GRIN2A

DIOPT Version :9

• Sequence 1: NP_572406.1
• Gene: Ir7a / 31686
• FlyBaseID: FBgn0029961
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_016878661.1
• Gene: GRIN2A / 2903
• HGNCID: 4585
• Length: 1516
• Species: Homo sapiens
• Alignment Length: 686
• Identity: 123/686 - (17%)
• Similarity: 243/686 - (35%)
• Gaps: 186/686 - (27%)

  Fly    54 LTQDAEHRDERQEQLMTIILRSVGSEMALRTFQKPPAEVPASFVVFLVNSAQAFNTLGFHF---- 114
            :|.|....|.:.:    :.|:.:.|.:.|....|..|       |.:::.|::....|:.|
Human   256 ITLDTSFEDAKTQ----VQLKKIHSSVILLYCSKDEA-------VLILSEARSLGLTGYDFFWIV 309

  Fly   115 -------TDIHSTREF-NFLI--------------------LLTHRMSSRAERLQVLRDISRTC- 150
                   |:: ..:|| :.||                    :||...||..|:...:.:...:|
Human   310 PSLVSGNTEL-IPKEFPSGLISVSYDDWDYSLEARVRDGIGILTTAASSMLEKFSYIPEAKASCY 373

  Fly   151 -------VRFHTSNVILLTEKRDGVVLVY---AYR--------LLNMDCDLSVNLELIDIYKNGL 197
                   |..||.:..::....||..|.:   .|:        :||.|.:    .|.:..::|..
Human   374 GQMERPEVPMHTLHPFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDRE----WEKVGKWENHT 434

  Fly   198 FRHGHEARSFNRVLSLSGCP-----LQVSWYPLPPFV--------------------SFIGNSSD 237
            ....|..  :.|..|.|.|.     |.:......|||                    .|:..::.
Human   435 LSLRHAV--WPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNS 497

  Fly   238 PEERAQIWR-LTGIDGELIKLLASIFDFRILLEEPCNKCLSPDIKDDCSGCFDQVIISNSSILIG 301
            ..|...:.: ..|...:::|.|:....|...|....|......:.:..:|...:|:...:.:.:|
Human   498 TNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVG 562

  Fly   302 AMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAV--PFTVIVW-----LALVVSSLLL 359
            :::.:.:......|:..:.::.:..::..|:  |.|:..|.  ||:..||     :.|:||::.:
Human   563 SLTINEERSEVVDFSVPFVETGISVMVSRSN--GTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 625

  Fly   360 VL------VLWMRN----RLVCGRSDLASHALQVLTTLMGNPLEARSLPRSSRLRILYAGWLLLV 414
            .:      |.:.||    :...|.|.....|:.:|..|:.|.......|:.:..:|:.:.|....
Human   626 FVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFA 690

  Fly   415 LVLRVVYQGKLF-----------------DSFRLP--YHKP-----LPTEISEL-IRSNYTLINQ 454
            ::....|...|.                 ..|:.|  |..|     :|...:|. ||:||..::|
Human   691 VIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQ 755

  Fly   455 EYLDYYPR----ELTVLTRNGSKDRF-------DYIQGLGKEGKFTTTS---LIATMEYYNMMH- 504
             |:..:.:    :..|..:.|..|.|       :|..|..:..|..|..   :.||..|...:.
Human   756 -YMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQK 819

  Fly   505 ---WSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREFDACQYRKPFE 566
               |        |..|.|          :||:|..|.::::|.:..:.|       .|...|
Human   820 GSPW--------KRQIDL----------ALLQFVGDGEMEELETLWLTG-------ICHNEK--- 856

  Fly   567 EDYEVTPIPLDSFCGLYYISLIWLSAAVVAFILELL 602
            .:...:.:.:|:..|::|:....::.:::.||.|.|
Human   857 NEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHL 892

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810