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Protein Alignment Ir7a and Grin2b

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_036706.1	Gene:	Grin2b / 24410	RGDID:	2738	Length:	1482	Species:	Rattus norvegicus

Alignment Length:	597	Identity:	104/597 - (17%)
Similarity:	200/597 - (33%)	Gaps:	172/597 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 LILLTHRMSSRAERLQVLRDISRTCVRFHTSNVILLTEKRDGVVLVYAYRLLNMDCDLSVNLE-- 188
            :.::|...|........:.:...:|...|        |||     :|...:||... ::|..|
  Rat   297 IAIITTAASDMLSEHSFIPEPKSSCYNTH--------EKR-----IYQSNMLNRYL-INVTFEGR 347

  Fly   189 LIDIYKNGLFRHG-------HEARSFNRVLSLSGCPLQVSWYPLP-------------------- 226
            .:...::|...|.       ::.|.:.||.......||:.:|..|
  Rat   348 NLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLE 412

  Fly   227 --PFVSFIGNSSDP-----------------------EERAQIWR-LTGIDGELIKLLASIFDFR 265
              |||  |..|.||                       ||...|.: ..|...:::|.::....|.
  Rat   413 EAPFV--IVESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVKFT 475

  Fly   266 ILLEEPCNKCLSPDIKDDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHM 330
            ..|....|......|....:|...:|::..:.:.:|:::.:.:......|:..:.::.:..::..
  Rat   476 YDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSR 540

  Fly   331 SSQFGAVAQLAV--PFTVIVW-----LALVVSSLLLVLVLWMR----NRLVC------GRSDLAS 378
            |:  |.|:..|.  ||:..||     :.|:||::.:.:..:..    ||.:.      |.|....
  Rat   541 SN--GTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIG 603

  Fly   379 HALQVLTTLMGNPLEARSLPRSSRLRILYAGWLLLVLVLRVVYQGKLF----------------- 426
            .|:.:|..|:.|.......|:.:..:|:.:.|....::....|...|.
  Rat   604 KAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSD 668

  Fly   427 ------DSFRLPYH-KPLPTEISEL-IRSNYT-------LINQEYLDYYPRELTVLTRNGSKDRF 476
                  :.|..|:. ..:|...:|. ||:||.       ..||..:|    :..:..:.|..|.|
  Rat   669 KKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVD----DALLSLKTGKLDAF 729

  Fly   477 -------DYIQGLGKEGKFTTT---SLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSL 531
                   :|:.|..:..|..|.   .:.|:..|                       .|.:::.|.
  Rat   730 IYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGY-----------------------GIAIQKDSG 771

  Fly   532 LKFAFDRKIKQLLSAGIIGYFVREFDA------CQYRKPFEEDYEVTPIPLDSFCGLYYISLIWL 590
            .|...|..|.||...|    .:.|.:|      |...|   .:...:.:.:|:..|::|:....:
  Rat   772 WKRQVDLAILQLFGDG----EMEELEALWLTGICHNEK---NEVMSSQLDIDNMAGVFYMLGAAM 829

  Fly   591 SAAVVAFILELL 602
            :.:::.||.|.|
  Rat   830 ALSLITFICEHL 841

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.