DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7a and W02A2.5

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_502564.2	Gene:	W02A2.5 / 189098	WormBaseID:	WBGene00012190	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	361	Identity:	72/361 - (19%)
Similarity:	134/361 - (37%)	Gaps:	116/361 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 FTSSYHQSSL--VFIMHMSSQ-FGAVAQLAV-PFTVIVWLALVVSSLLLVLV----------LWM 365
            |..||..:::  ||:....:: .|:|...|. ||:|.|||.|:.|.:|.:|:          |..
Worm   107 FEYSYPVTNVQPVFVARKKTETLGSVLWNAFKPFSVEVWLCLLASLVLNLLIMIAISGIEFKLLF 171

  Fly   366 RNRLVCGRS-DLASHALQ----------VLTTLMGN-PLEARSLPRSSRLRILYAGWLLLVLV-- 416
            |:|.   |. ::..|.:|          :..||.|| .|...:|.:|..|..:|.|.||..|:
Worm   172 RSRF---RPWEMLWHVVQLQLDEKSDDMLFYTLSGNIVLFVFALLQSGILIEVYKGMLLTALITS 233

  Fly   417 ----------------------LRVVYQGK-LFDSFRLPYHKPLPTEIS---------------- 442
                                  |...|.|. .||..:   |......:|
Worm   234 NGDNPFANADEMIKLIGEKKYHLTTNYMGNWYFDDLQ---HSDQQHFVSLRAATASNPVIPAASV 295

  Fly   443 ----ELIRSNYTLINQEYLDYYPRELTVLTRNGSKDRFDYI---QGLGKEGKFTTTSLIATMEYY 500
                :|:.|.      :|:  ||.:...|....||:|.:|:   .|:.:...|    .:.|..:.
Worm   296 SAALDLVDSG------KYI--YPIQQDSLAMQMSKERCNYVYVSDGMPQVSSF----FVFTKNFS 348

  Fly   501 NMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREFDACQYRKPF 565
            .:..::|             |:::   ..:.::..|::...:....|.|       ..|:..:|.
Worm   349 GIAEFNT-------------QIIM---NQAFIQRTFNKYFNEGFKLGFI-------PKCEVTEPT 390

  Fly   566 EEDYEVTPIPLDSFCGLYYISLIWLSAAVVAFILEL 601
            ..| ...|:.::|..|::.|..:.::|:::.|:.|:
Worm   391 ASD-ATKPLDIESVIGVFTIGALGVAASLMVFVFEI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
W02A2.5	NP_502564.2	Lig_chan-Glu_bd	<36..86	CDD:214911
W02A2.5	NP_502564.2	Periplasmic_Binding_Protein_Type_2	<74..>124	CDD:304360	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900