Protein Alignment Ir7a and grin2cb

DIOPT Version :9

• Sequence 1: NP_572406.1
• Gene: Ir7a / 31686
• FlyBaseID: FBgn0029961
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_009305071.2
• Gene: grin2cb / 100333648
• ZFINID: ZDB-GENE-100308-2
• Length: 1328
• Species: Danio rerio
• Alignment Length: 617
• Identity: 115/617 - (18%)
• Similarity: 208/617 - (33%)
• Gaps: 200/617 - (32%)

  Fly   153 FHTSNVILLTEK---------RDGVVLV-------YAYRLL----NMDCDLSVNLELIDIYKNGL 197
            |....:.::|::         |:||.::       :.:|..    :.||...|.    ....|.|
Zfish   278 FPVGVISIITDRWRKTLRQRVREGVAIIVKGVHSFHKHRGFIPEGHSDCSSPVK----SYANNSL 338

  Fly   198 FRH------GHEARSFN----------------------RVLSLSGCPLQVSWYPLPPFVSF--- 231
            |||      .|:..|||                      :|.|..|..||:.:...|.:.||
Zfish   339 FRHMLNVSWEHKDLSFNSDGYLTNPSMVIIALDRENHWDKVGSYEGGILQMRYPVWPRYGSFLEP 403

  Fly   232 ------------------IGNSSDPEE----------RAQIWRLTGIDG---------------E 253
                              |..|.||..          |.|..|...|.|               :
Zfish   404 VSDNRHLTVATLEERPFVIVESVDPATGTCVRNTVPCRRQSNRTESIIGHTEPYTKLCCKGFCID 468

  Fly   254 LIKLLASIFDFRILLEEPCNKCLSPDIKDDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSS 318
            ::|.|:....|...|....|......::...:|...:|....:.:.||:::.:.:......|:..
Zfish   469 ILKKLSRTIKFSYDLYLVTNGKHGKMVRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVP 533

  Fly   319 YHQSSLVFIMHMSSQFGAVAQLAV--PFTVIVWLALVVSSLLLVLV----------LWMRNRLVC 371
            :.::.:..::..|:  |.|:..|.  |::..||:.:.|..|.:|.|          :.....||.
Zfish   534 FVETGISVMVARSN--GTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVS 596

  Fly   372 -----GRSDLASHALQVLTTLMGN---PLEARSLPRSSRLRILYAGWLLLVLVLRVVY------- 421
                 |.:.....::.:|..::.|   |:|.   |:.:..:|:...|....::....|
Zfish   597 AKAPGGPTFTIGKSVWLLWGIVFNNSVPIEN---PKGTTSKIMVLVWAFFAVIFLASYTANLAAF 658

  Fly   422 --QGKLFDS--------FRLPY-HKP------LPTEISEL-IRSNYTLINQEYLDYYPR---ELT 465
              |.:..|:        |:.|. |.|      :|...:|. |||||..::...:.|..:   |..
Zfish   659 MIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEAL 723

  Fly   466 VLTRNGSKDRF-------DYIQG---------LGKEGKFTTTSLIATMEYYNMMHWSTSRLTHIK 514
            ...:.|..|.|       :|:.|         :|....|.||.       |.:.....||.   |
Zfish   724 NSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTG-------YGIALQKDSRW---K 778

  Fly   515 EHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREFDACQYRKPFEEDYEVTPIPLDSF 579
            ..|.|          :||:|..|...::|.:..:.|       .||..|   .:...:.:.:|:.
Zfish   779 RPIDL----------ALLQFLGDGDTQRLETVWLSG-------ICQNEK---NEVMSSKLDIDNM 823

  Fly   580 CGLYYISLIWLSAAVVAFILELLSQRIVWLRR 611
            .|::|:.|:.:..:::.|..|.|   :.|..|
Zfish   824 AGVFYMLLVAMGLSLLVFAWEHL---LYWKLR 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
grin2cb	XP_009305071.2	PBP1_iGluR_NMDA_NR2	37..396	CDD:107373	23/121 (19%)
		PBP2_iGluR_NMDA_Nr2	407..808	CDD:270436	78/432 (18%)
		NMDAR2_C	845..>932	CDD:313729	3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900