DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7a and LOC100149482

DIOPT Version :9

Sequence 1:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_009290417.1	Gene:	LOC100149482 / 100149482	-ID:	-	Length:	1959	Species:	Danio rerio

Alignment Length:	425	Identity:	81/425 - (19%)
Similarity:	155/425 - (36%)	Gaps:	106/425 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 ELIKLLASIFDFRILLEEPCNKCLSPDIKDDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTS 317
            :::|.||.|..|...|....|......|....:|...:|:...:.:.||:::.:.:......|:.
Zfish   491 DILKRLARIVGFTYDLYLVTNGKHGKKIDGVWNGMVGEVVYKRADMAIGSLTINEERSEVVDFSV 555

  Fly   318 SYHQSSLVFIMHMSSQFGAVAQLAV--PFTVIVWLALVVSSLLLVLV----------LWMRNRLV 370
            .:.::.:..::..|:  |.|:..|.  |::..||:.:.|..|.:|.|          :.....|.
Zfish   556 PFVETGISVMVSRSN--GTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEFFSPVGYNRSLQ 618

  Fly   371 CGRSDLAS-----HALQVLTTLMGN---PLEARSLPRSSRLRILYAGWLLLVLVLRVVY------ 421
            .|:....|     .::.:|..|:.|   |:|.   |:.:..:|:...|....::....|
Zfish   619 SGKKAGGSKFTIGKSIWLLWALVFNNSVPVEN---PKGTTSKIMVLVWAFFAVIFLASYTANLAA 680

  Fly   422 ---QGKLFDS--------FRLPYHKPLPTEISEL--------IRSNYTLINQ---EY-------- 456
               |.:..|:        |:.|..:..|.:...:        |||||..::|   :|
Zfish   681 FMIQEEYIDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYPDMHQYMVKYNQKSVEDA 745

  Fly   457 --------LDYYPRELTVLTRNGSKDRFDYIQGLGKEGKFTTTSLIATMEYYNMMHWSTSRLTHI 513
                    ||.:..:..||.....||....:..:|....|.||.       |.:.....||.
Zfish   746 ISHLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTG-------YGIALIKNSRW--- 800

  Fly   514 KEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREFDACQYRKPFEEDYEV--TPIPL 576
            |..:.|          :||:...|.:|:.|....:.|       .|.     .:..||  :.:.:
Zfish   801 KRPLDL----------ALLQLVGDDEIEMLERLWLSG-------ICH-----NDKIEVMSSKLDI 843

  Fly   577 DSFCGLYYISLIWLSAAVVAFILELLSQRIVWLRR 611
            |:..|::|:.|:.:..:::.|..|.|   :.|..|
Zfish   844 DNMAGVFYMLLVAMGLSLLVFAWEHL---VYWRLR 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
LOC100149482	XP_009290417.1	PBP1_iGluR_NMDA_NR2	44..421	CDD:107373
		PBP2_iGluR_NMDA_Nr2	433..831	CDD:270436	70/376 (19%)
		HisJ	<487..>570	CDD:223904	13/78 (17%)
		Lig_chan	585..857	CDD:278489	58/306 (19%)
		NMDAR2_C	868..>900	CDD:287527	3/11 (27%)
		FAM76	<1763..>1856	CDD:292665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900