Protein Alignment Ir7a and grin2ca

DIOPT Version :9

• Sequence 1: NP_572406.1
• Gene: Ir7a / 31686
• FlyBaseID: FBgn0029961
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001352716.1
• Gene: grin2ca / 100003342
• ZFINID: ZDB-GENE-070822-3
• Length: 1400
• Species: Danio rerio
• Alignment Length: 641
• Identity: 120/641 - (18%)
• Similarity: 203/641 - (31%)
• Gaps: 248/641 - (38%)

  Fly   153 FHTSNVILLTEK---------RDGVVLVY----AYRLL-------NMDCDLSVNLELIDIYKNG- 196
            |....:.::|::         ||||.:|.    ::|..       :|||     |..|....||
Zfish   280 FPVGLISIITDRWKMSLRNRVRDGVAIVVKGVESFRKQRGFIPDGHMDC-----LSPIRPASNGT 339

  Fly   197 LFRHGHEARSFNRVLSLSGCPLQVSW-----------YPLPPFVSFI-----------GN--SSD 237
            |:||                .|.|||           |.:.|.:..|           ||  |..
Zfish   340 LYRH----------------MLNVSWENTDFSFNSDGYLVNPSMIIITLDRGRQWDKVGNYESGI 388

  Fly   238 PEERAQIWRLTGIDGELIKLLASIFDFRIL----LEE---------------------PC----N 273
            .:.|..:|...|      ..|..:.|.|.|    |||                     ||    |
Zfish   389 LQMRYPVWPRYG------TFLEPVSDNRHLTVATLEERPFVIVEAVDPVTGTCLSNTVPCRRQSN 447

  Fly   274 KC------LSPDIKDDCSG-CFD------------------------------------QVIISN 295
            |.      ..|..|..|.| |.|                                    :|....
Zfish   448 KTETIVGHTEPYTKLCCKGFCIDILKKLSRNIKFSYDLYLVTNGKHGKLVRGIWNGMIGEVFYKR 512

  Fly   296 SSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAV--PFTVIVWLALVVSSLL 358
            :.:.||:::.:.:......|:..:.::.:..::..|:  |.|:..|.  |::..||:.:.|..|.
Zfish   513 ADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSN--GTVSPSAFLEPYSPAVWVMMFVMCLT 575

  Fly   359 LVLVLWM---------RNRLVCGRSD------LASHALQVLTTLMGN---PLEARSLPRSSRLRI 405
            :|.|...         .||.:....|      ....::.:|..::.|   |:|.   |:.:..:|
Zfish   576 VVAVTVFVFEYCSPVGYNRSLVSAKDPGGPTFTIGKSVWLLWGIVFNNSVPIEN---PKGTTSKI 637

  Fly   406 LYAGWLLLVLVLRVVYQGKLFDSFRL--------------PYHKP-----------LPTEISEL- 444
            :...|....::....|...| .:|.:              .:.||           :|...:|.
Zfish   638 MVLVWAFFAVIFLASYTANL-AAFMIQEQYIDTVSGLSDKKFQKPQDQYPPFRFGTVPNGSTERN 701

  Fly   445 IRSNY-------TLINQE------------YLDYYPRELTVLTRNGSKDRFDYIQGLGKEGKFTT 490
            |||||       ...||:            .||.:..:..||.....||....:..:|....|.|
Zfish   702 IRSNYPEMHSHMVKYNQKGVEDALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFAT 766

  Fly   491 TSLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVRE 555
            |.       |.:.....||.   |..|.|          :||:|..|...::|.:..:.|
Zfish   767 TG-------YGIALQKESRW---KRPIDL----------ALLQFLADGDTQKLQTVWLTG----- 806

  Fly   556 FDACQYRKPFEEDYEVTPIPLDSFCGLYYISLIWLSAAVVAFILELLSQRIVWLRR 611
              .|:..|   ::...:.:.:|:..|::|:.|:.:..:::.|..|.|   :.|..|
Zfish   807 --ICRNEK---KEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHL---LYWKLR 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7a	NP_572406.1	None
grin2ca	NP_001352716.1	PBP1_iGluR_NMDA_NR2	38..398	CDD:107373	30/138 (22%)
		PBP2_iGluR_NMDA_Nr2	409..810	CDD:270436	77/433 (18%)
		NMDAR2_C	847..>938	CDD:313729	3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900