Protein Alignment Rab39 and RAB27A

DIOPT Version :10

• Sequence 1: NP_572405.2
• Gene: Rab39 / 31684
• FlyBaseID: FBgn0029959
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_004571.2
• Gene: RAB27A / 5873
• HGNCID: 9766
• Length: 221
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 79/222 - (35%)
• Similarity: 123/222 - (55%)
• Gaps: 18/222 - (8%)

  Fly     6 FEYQFRLILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLIEMK---------DGTQIKL 61
            ::|..:.:.:|||.|||:|:|..:|||||......|||:||..:.:..:         .|.:|.|
Human     6 YDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70

  Fly    62 QLWDTAGQERFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEPHRPVFALVGCKL 126
            |||||||||||||:|.:::|:::|.||::|::|..||.::..|:.:.|.|.....|...|.|.|.
Human    71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKS 135

  Fly   127 DLINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYARIRSGEYKAEDGWD 191
            ||.:   .|.|..|||...|:::|:.:.||||.:|.|:.:|..|:...:..|:   |...:..|
Human   136 DLED---QRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRM---ERCVDKSW- 193

  Fly   192 GIKSGFSRPNS-LDFNLVVAEPEKSSC 217
             |..|..|.|. ...:.:..|.||.:|
Human   194 -IPEGVVRSNGHASTDQLSEEKEKGAC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab39	NP_572405.2	Rab39	8..218	CDD:133311	79/220 (36%)
RAB27A	NP_004571.2	Rab27A	6..185	CDD:206700	68/181 (38%)
		Effector region. /evidence=ECO:0000250	38..46		3/7 (43%)