DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab39 and Rab39

DIOPT Version :9

Sequence 1:	NP_001245568.1	Gene:	Rab39 / 31684	FlyBaseID:	FBgn0029959	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_780771.1	Gene:	Rab39 / 270160	MGIID:	2442855	Length:	217	Species:	Mus musculus

Alignment Length:	221	Identity:	118/221 - (53%)
Similarity:	159/221 - (71%)	Gaps:	8/221 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VEPIFEYQFRLILIGDSTVGKSSLLKFFTDGKFAEL----SDPTVGVDFFARLIEMKDGTQIKLQ 62
            :|.|:.||||||:|||||||||.||..||.|:|..|    .|||||||||:||:|::.|.:||||
Mouse     1 METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLHSPACDPTVGVDFFSRLLEIEPGKRIKLQ 65

  Fly    63 LWDTAGQERFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEPHRPVFALVGCKLD 127
            ||||||||||||||:||||||||..||:||:|..||||:..|:.||:.|::|.:.||.|||.|.|
Mouse    66 LWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCD 130

  Fly   128 LINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYARIRSGEYKAEDGWDG 192
            |   ...|:|:.|||::.:...|:.::||||:...||||:|.::|:::|..|:.||...:|||:|
Mouse   131 L---ASQRQVSREEAERLSTDCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEG 192

  Fly   193 IKSGFSRPNSLDFNLVVAEPEKSSCC 218
            :||||. ||::..:....:|.|...|
Mouse   193 VKSGFV-PNTVHSSEEAVKPRKECFC 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab39	NP_001245568.1	Rab39	8..218	CDD:133311	115/213 (54%)
Rab39	NP_780771.1	Rab39	7..217	CDD:133311	115/213 (54%)
		RAB	9..176	CDD:197555	97/170 (57%)
		Effector region. /evidence=ECO:0000250	41..49		6/7 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I3034
eggNOG	1	0.900	-	-		E2759_KOG0091
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3386
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1416096at2759
OrthoFinder	1	1.000	-	-		FOG0003983
OrthoInspector	1	1.000	-	-		otm42739
orthoMCL	1	0.900	-	-		OOG6_105997
Panther	1	1.100	-	-	O	PTHR47979
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3742
SonicParanoid	1	1.000	-	-		X2743
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.860