Protein Alignment Pdp and PPM1D

DIOPT Version :9

• Sequence 1: NP_001245567.1
• Gene: Pdp / 31683
• FlyBaseID: FBgn0029958
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_003611.1
• Gene: PPM1D / 8493
• HGNCID: 9277
• Length: 605
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 79/332 - (23%)
• Similarity: 121/332 - (36%)
• Gaps: 118/332 - (35%)

  Fly    72 CEDSRTEASFLHRNGFICGIFDGHAGAACGQVVSKRLLRYVS-----AATLPRQVLREQMKQGAD 131
            |...|:..:|.       .:.|||.|....|...:.|..::.     .::.|.:|.      .|.
Human    91 CCRRRSSVAFF-------AVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVC------AAI 142

  Fly   132 SQSFLKCHNDNVDFVSMIKPMYEASFLKYVNQLLETPQRDVSSELVNAFLQLDEEISQEALTSND 196
            .:.||.||      ::|.|            :|.|.|
Human   143 RKGFLACH------LAMWK------------KLAEWP---------------------------- 161

  Fly   197 VRTMN--VALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDP---------QTQQWHSKKLNIEH 250
             :||.  .:.||..|.:|.|.|::|:||..||.|.|||:.|.         :..|.|..:|..|.
Human   162 -KTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKER 225

  Fly   251 --------NADNMSEVRRILAEHPKEEHETVIRNGRLLSQ---LAPLRAFGDFRYKWSQEIMQQK 304
                    :..|.|.|.|::.:.|:..|...:|...::.|   ||..||.||.   ||.:...
Human   226 ERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL---WSYDFFS-- 285

  Fly   305 VLPMFGVQAMAPNYYTPPYLTARPDVQQHELGP-NDKFLVIASDGLWDFLPPSEVVS-------- 360
                 |...::|          .||...|.|.| ..|::::.|||||:.:||.:.:|
Human   286 -----GEFVVSP----------EPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEK 335

  Fly   361 --LVGEH 365
              |:|||
Human   336 KYLMGEH 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	79/332 (24%)
PPM1D	NP_003611.1	Interaction with CHEK1. /evidence=ECO:0000269|PubMed:15870257	1..101		2/9 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..90
		PP2C	67..368	CDD:278884	79/332 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..591

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810