DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdp and Ilkap

DIOPT Version :9

Sequence 1:	NP_001245567.1	Gene:	Pdp / 31683	FlyBaseID:	FBgn0029958	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_072128.2	Gene:	Ilkap / 64538	RGDID:	620128	Length:	392	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	76/368 - (20%)
Similarity:	143/368 - (38%)	Gaps:	97/368 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 IRSYETNQLGSNWPCEDSRT-----------EASFLHRNGFICGIFDGHAGAACGQVVSKRLLRY 111
            ::.|...:.|.....:|:..           .:|.:.|..:. .:||||.|....:..::.|
  Rat   107 LKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYF-AVFDGHGGIRASKFAAQNL--- 167

  Fly   112 VSAATLPRQVLREQMKQGADSQSFLKCHNDNVDFVSMIKPMYEASFLKYVNQLLETPQRDVSSEL 176
                   .|.|..:..:|              |.:|:                    ::.|...|
  Rat   168 -------HQNLIRKFPKG--------------DVISV--------------------EKTVKRCL 191

  Fly   177 VNAFLQLDEEISQEALTSNDVRTMNVALSGAVA-CLVHIEGLQMHVASTGDCGAVLGVLDPQTQQ 240
            ::.|...|||..::|.:......     .|:.| |::.::.: :::|:.||..|:|...:.::|:
  Rat   192 LDTFKHTDEEFLKQASSQKPAWK-----DGSTATCVLAVDNI-LYIANLGDSRAILCRYNEESQK 250

  Fly   241 WHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKV 305
            ..:..|:.|||.....|..||      ::....:|:||:|..|...|:.||.:||
  Rat   251 HAALSLSKEHNPTQYEERMRI------QKAGGNVRDGRVLGVLEVSRSIGDGQYK---------- 299

  Fly   306 LPMFGVQAMAPNYYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKK 370
              ..||             |:.||:::.:|.|||:|:::|.|||:....|.|.|:.:...:..:|
  Rat   300 --RCGV-------------TSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEK 349

  Fly   371 ILEPMRLPEGDTTLQEISQQLAERKAGLTRKPVDQNAATHLIR 413
            |......|..|...:....:||.:  .:.|...| |....::|
  Rat   350 IQTREGKPAVDARYEAACNRLANK--AVQRGSAD-NVTVMVVR 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	72/347 (21%)
Ilkap	NP_072128.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91
Ilkap	NP_072128.2	PP2Cc	108..390	CDD:238083	76/367 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810