DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pdp and Pdp1

DIOPT Version :9

Sequence 1:	NP_001245567.1	Gene:	Pdp / 31683	FlyBaseID:	FBgn0029958	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	XP_006237970.1	Gene:	Pdp1 / 54705	RGDID:	620393	Length:	578	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	185/467 - (39%)
Similarity:	275/467 - (58%)	Gaps:	31/467 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PQLPQLSPYDVNLVLRENEFVYNFP-VDG----VIRSYETNQLGSNWPCEDSRTEASFLHRNGFI 88
            ||...|:|..||.:|:.||:.:..| .||    .|..:::|||.:|.|.||.|:.|:.|...|.:
  Rat   115 PQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGML 179

  Fly    89 CGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLRE---QMKQGADSQSFLKCHNDNVDFVSM-I 149
            .|:||||||.||.|.||:||..|::.:.||.:.|.|   .::.|......|:.|....|:.|. .
  Rat   180 LGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEA 244

  Fly   150 KPMYEASFLKYVNQLL-----ETPQRDVSSELVNAFLQLDEEISQEALTSNDVRTMN-----VAL 204
            ..:|..|...|..:|:     |:...||...|:|||.:||.:||.||...:....:|     ||.
  Rat   245 SKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAF 309

  Fly   205 SGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEE 269
            |||.||:.|::|:.:|||:|||..|:|||.: :...|.:..|:.:|||.|..|:.|:..||||.|
  Rat   310 SGATACVAHVDGVDLHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKNE 373

  Fly   270 HETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFGVQA--------MAPNYYTPPYLTA 326
            .::|::..|||..|.|.|||||.::|||.: :|::|:.....|.        :.|||:|||||||
  Rat   374 AKSVVKQDRLLGLLMPFRAFGDVKFKWSID-LQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTA 437

  Fly   327 RPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTTLQEISQQL 391
            .|:|..|.|.|.|||||:|:||||:.:...:||.:|||::......:|:.:.....||.::...|
  Rat   438 EPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLL 502

  Fly   392 AERKAGLTRKPVDQNAATHLIRHALGGTDYG-IEHSKISYYLTLPRDAVRLYRDDITITVIYFNS 455
            .||:|.::....||||||||||||:|..::| ::|.::|..|:||.:..|:|||||||.|:.|||
  Rat   503 TERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNS 567

  Fly   456 EHIAKLHSDVDQ 467
             |:...:.:.:|
  Rat   568 -HVVGAYQNQEQ 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	137/357 (38%)
Pdp1	XP_006237970.1	PP2Cc	149..565	CDD:238083	168/417 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338462
Domainoid	1	1.000	177	1.000	Domainoid score	I3493
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31928
Inparanoid	1	1.050	317	1.000	Inparanoid score	I2466
OMA	1	1.010	-	-		QHG52867
OrthoDB	1	1.010	-	-		D186269at33208
OrthoFinder	1	1.000	-	-		FOG0002436
OrthoInspector	1	1.000	-	-		otm46380
orthoMCL	1	0.900	-	-		OOG6_101170
Panther	1	1.100	-	-	LDO	PTHR13832
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X558
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770