Protein Alignment Pdp and PDP1

DIOPT Version :9

• Sequence 1: NP_001245567.1
• Gene: Pdp / 31683
• FlyBaseID: FBgn0029958
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_016869077.1
• Gene: PDP1 / 54704
• HGNCID: 9279
• Length: 591
• Species: Homo sapiens
• Alignment Length: 458
• Identity: 183/458 - (39%)
• Similarity: 270/458 - (58%)
• Gaps: 31/458 - (6%)

  Fly    29 PQLPQLSPYDVNLVLRENEFVYNFP-VDG----VIRSYETNQLGSNWPCEDSRTEASFLHRNGFI 88
            ||...|:|..||.:|:.||:.:..| .||    .|..:::|||.:|.|.||.|:.|:.|...|.:
Human   129 PQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGML 193

  Fly    89 CGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLRE---QMKQGADSQSFLKCHNDNVDFVSM-I 149
            .|:||||||.||.|.||:||..|::.:.||.:.|.|   .::.|......|:.|....|:.|. .
Human   194 LGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEA 258

  Fly   150 KPMYEASFLKYVNQLL-----ETPQRDVSSELVNAFLQLDEEISQEALTSNDVRTMN-----VAL 204
            ..:|..|...|..:|:     |:...||...|:|||.:||.:||.||...:....:|     ||.
Human   259 SKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAF 323

  Fly   205 SGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEE 269
            |||.||:.|::|:.:|||:|||..|:|||.: :...|.:..|:.:|||.|..|:.|:..||||.|
Human   324 SGATACVAHVDGVDLHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKSE 387

  Fly   270 HETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFGVQA--------MAPNYYTPPYLTA 326
            .::|::..|||..|.|.|||||.::|||.: :|::|:.....|.        :.|||:|||||||
Human   388 AKSVVKQDRLLGLLMPFRAFGDVKFKWSID-LQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTA 451

  Fly   327 RPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTTLQEISQQL 391
            .|:|..|.|.|.|||||:|:||||:.:...:||.:|||::......:|:.:.....||.::...|
Human   452 EPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLL 516

  Fly   392 AERKAGLTRKPVDQNAATHLIRHALGGTDYG-IEHSKISYYLTLPRDAVRLYRDDITITVIYFNS 455
            .||:..::....||||||||||||:|..::| ::|.::|..|:||.:..|:|||||||.|:.|||
Human   517 TERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNS 581

  Fly   456 EHI 458
             |:
Human   582 -HV 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	137/357 (38%)
PDP1	XP_016869077.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144767
Domainoid	1	1.000	176	1.000	Domainoid score	I3625
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31928
Inparanoid	1	1.050	318	1.000	Inparanoid score	I2544
Isobase	1	0.950	-	0	Normalized mean entropy	S2687
OMA	1	1.010	-	-		QHG52867
OrthoDB	1	1.010	-	-		D186269at33208
OrthoFinder	1	1.000	-	-		FOG0002436
OrthoInspector	1	1.000	-	-		otm42227
orthoMCL	1	0.900	-	-		OOG6_101170
Panther	1	1.100	-	-	LDO	PTHR13832
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4300
SonicParanoid	1	1.000	-	-		X558
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750