DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdp and PPM1J

DIOPT Version :9

Sequence 1:	NP_001245567.1	Gene:	Pdp / 31683	FlyBaseID:	FBgn0029958	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_005158.5	Gene:	PPM1J / 333926	HGNCID:	20785	Length:	505	Species:	Homo sapiens

Alignment Length:	423	Identity:	89/423 - (21%)
Similarity:	159/423 - (37%)	Gaps:	146/423 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 PCEDSRTEASFLHRNGFIC----GIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGAD 131
            |.|.||.:.        :|    |:||||||....::.|:.|.|::          |||:|   |
Human   140 PREPSRGQG--------LCFYYWGLFDGHAGGGAAEMASRLLHRHI----------REQLK---D 183

  Fly   132 SQSFLKCHN-------------DNVDFVSMIKPMYEASFLKYVNQLLETPQRDVSSE------LV 177
            ....|:..:             |:.|...::.|           |...:.|::||.|      :.
Human   184 LVEILQDPSPPPLCLPTTPGTPDSSDPSHLLGP-----------QSCWSSQKEVSHESLVVGAVE 237

  Fly   178 NAFLQLDEEISQEALTSNDVRTMNVALSGAVACLV-HIEGLQMHVASTGDCGAVL---GVL---- 234
            |||..:||::::|       |..:....|..|.:| ::.| :::||:.||..|::   |.:
Human   238 NAFQLMDEQMARE-------RRGHQVEGGCCALVVIYLLG-KVYVANAGDSRAIIVRNGEIIPMS 294

  Fly   235 ---DPQTQQWHSKKLN------IEHNADNMSEVRRILAEHPKEEHETVI---------------- 274
               .|:|::...:.|.      :.....::...||:|   |||..:.::
Human   295 REFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVL---PKELGQRMLYRDQNMTGWAYKKIEL 356

  Fly   275 ------------RNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFGVQAMAPNYYTPPYLTAR 327
                        :..|:::.:...|..||...|     :....||:            .|:|:..
Human   357 EDLRFPLVCGEGKKARVMATIGVTRGLGDHSLK-----VCSSTLPI------------KPFLSCF 404

  Fly   328 PDVQ-----QHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTTLQEI 387
            |:|:     |:|..|:| .||:.:|||||.....||.:.|...:::.:       |...:....:
Human   405 PEVRVYDLTQYEHCPDD-VLVLGTDGLWDVTTDCEVAATVDRVLSAYE-------PNDHSRYTAL 461

  Fly   388 SQQLAERKAGLTRKPVDQNAATHLIRHALGGTD 420
            :|.|.....|..|     :....|..:.||..|
Human   462 AQALVLGARGTPR-----DRGWRLPNNKLGSGD 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	83/395 (21%)
PPM1J	NP_005158.5	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..103
PPM1J	NP_005158.5	PP2Cc	106..498	CDD:238083	89/423 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840