DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdp and Ppm1g

DIOPT Version :9

Sequence 1:	NP_001245567.1	Gene:	Pdp / 31683	FlyBaseID:	FBgn0029958	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_032040.1	Gene:	Ppm1g / 14208	MGIID:	106065	Length:	542	Species:	Mus musculus

Alignment Length:	314	Identity:	69/314 - (21%)
Similarity:	121/314 - (38%)	Gaps:	74/314 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGADSQSFLKCHNDNVDFVSMIKPMYE 154
            |...|.||.:|.....|          |||....:..:...|....::...|:.:..|..:..|.
Mouse   231 GTATGEAGPSCSSASDK----------LPRVAKSKFFEDSEDESDEVEEEEDDSEECSEDEDGYS 285

  Fly   155 ASFLKYVNQLLETPQRDVSSELVNAFLQLDEEISQEALTSNDVRTMNVAL---------SGAVAC 210
                              |.|..|   :.||:.::||...:|...|...:         ||..|.
Mouse   286 ------------------SEEAEN---EEDEDDTEEAEEDDDEEMMVPGMEGKEEPGSDSGTTAV 329

  Fly   211 LVHIEGLQMHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIR 275
            :..|.|.|:.||:.||...|:      ::...:..::.:|..::..|:.||     |.....|..
Mouse   330 VALIRGKQLIVANAGDSRCVV------SEAGKALDMSYDHKPEDEVELARI-----KNAGGKVTM 383

  Fly   276 NGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFGVQAMAPNYYTPPYLTARPDVQQHELGPNDK 340
            :||:...|...||.||..||.::.:..|:.:                 ::|.||::...|..:.:
Mouse   384 DGRVNGGLNLSRAIGDHFYKRNKNLPPQEQM-----------------ISALPDIKVLTLTDDHE 431

  Fly   341 FLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTTLQEISQQLAER 394
            |:|||.||:|:.:...|||..:...|:.:.....:||      |..|.::|.::
Mouse   432 FMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRL------LSSIVEELLDQ 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdp	NP_001245567.1	PP2Cc	58..394	CDD:238083	69/312 (22%)
Ppm1g	NP_032040.1	PP2Cc	25..>110	CDD:214625
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..325		22/124 (18%)
		PP2Cc	<321..502	CDD:238083	47/193 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	513..542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900