DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12155 and CG8765

DIOPT Version :9

Sequence 1:	NP_572403.1	Gene:	CG12155 / 31682	FlyBaseID:	FBgn0029957	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_649141.1	Gene:	CG8765 / 40147	FlyBaseID:	FBgn0036900	Length:	690	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	101/432 - (23%)
Similarity:	161/432 - (37%)	Gaps:	100/432 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSSTQERKRYHKDNAPTDDILT--------LINLVRQNPVLYNYKLQPNQRRRSDVLNGWQEVAQ 58
            ::..|......:|:.|....|.        ||.|::|..::|||. ..|.|.....:..|:|:|:
  Fly   289 AAHNQSTNAEEEDDDPIHTFLNMESYFEKELITLIQQEDMIYNYG-NENYRNAKLKMEVWEEIAR 352

  Fly    59 QIGNKYTVQEVRRKWKNLRDTF---HQYRLRTPKYIEGRLSKWRYAKELDFLSKVYQPKLKSHRN 120
            ::  |.:|::.|.|||.|||.:   |: ||||..:|:. .|:|::...|.||.|..|.|
  Fly   353 KL--KKSVKQCRLKWKALRDQYAREHK-RLRTLMHIDA-TSRWKHYNSLSFLQKYIQQK------ 407

  Fly   121 TQITYETSGVAGAGGGIGGANSTTLPIGAMLHLKQHVDDDDDEVMDDDGQSDHDTATLSSHH-GT 184
                                   ||...:.|.:....:|...|:      .||.|   .||. .|
  Fly   408 -----------------------TLESDSQLSMLLPKNDPVREL------EDHMT---QSHSPPT 440

  Fly   185 SQITLVSDEAETFILTAYEEGVSDDTVSQHHHHHHHGHHQQEHHHQPHHHHHHHHHQSQHDGSIS 249
            .||||.|..:.:.:         :.....|....|....||:...|...|.....||.|.....:
  Fly   441 QQITLESSSSNSQL---------NLPTLPHLTGPHKAEQQQQQQQQEEQHQQQQQHQQQQQQQQA 496

  Fly   250 SIELSQIAHDDDVVD-----DVDDEDDVVDHDGQLDIVKHELDEDGATGAEVDYEE----VCLYE 305
            | ||....:||..::     ||...||.|:.|       .:.:.:..|.||...::    |..|:
  Fly   497 S-ELCVATYDDMDIENYINGDVHHNDDDVEDD-------EDEEMETTTAAEQPPQQQDQHVMTYD 553

  Fly   306 EASGAHVDCEIGVGDAVDGGSDVTHG----KGFHYIDTHEFCISDIEPQTVRSSQHQFSASGGSG 366
            ...|........||.|:.....::.|    :......|.||  ..||.||..:.::|.:|:..|.
  Fly   554 HEDGPVYMAVPSVGSAMSKQEQLSDGATSLENQQLQSTAEF--QKIEIQTPTTPRYQNAATTPSS 616

  Fly   367 NGSNSVLTGGTVVTDGKVKNLTLVTTTSPAAGGGGSTNRHDS 408
            ..::..             :...:|.:.|......|:|.|:|
  Fly   617 TSTSRY-------------HSAPITPSKPTHMEYPSSNGHNS 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12155	NP_572403.1	MADF	24..112	CDD:214738	33/90 (37%)
CG8765	NP_649141.1	MADF	42..123	CDD:214738
CG8765	NP_649141.1	MADF	318..405	CDD:214738	33/91 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I8335
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910