Protein Alignment NELF-B and nelfb

DIOPT Version :9

• Sequence 1: NP_572402.1
• Gene: NELF-B / 31681
• FlyBaseID: FBgn0027553
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001011448.1
• Gene: nelfb / 496936
• XenbaseID: XB-GENE-5814644
• Length: 576
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 298/576 - (51%)
• Similarity: 406/576 - (70%)
• Gaps: 9/576 - (1%)

  Fly    14 GLEDVNIPGQAYLREALTSCTDPLKAIESFQLENGVLLPSLRPMLPLLDLHGVRRLDFHTSLMEE 78
            ||.::.:.....|:|.||:||:||||||.||:|||||||||:..||.||||.:.||:||.:::||
 Frog     4 GLSELGVANGEELKETLTNCTEPLKAIEQFQIENGVLLPSLQSALPFLDLHSIPRLEFHQTVLEE 68

  Fly    79 LRDKLIAHINEM-GQKEPRERDKKLKELLVKSFPVVRVKSLRPVVMAILRNTQHIDDKYLKILVR 142
            ||:||:..:..: .:.:...|..||:|||.|.|.:|::.|::||||.::::...:.:|.||:::.
 Frog    69 LREKLLERVTAIAAEGKDGGRYGKLEELLEKCFALVKMPSIQPVVMCVMKHLPKVPEKKLKLVMA 133

  Fly   143 DRELYADTDTEVKRQIWRDNQSLFGDEVSPLLSQYIREKEHILF--DHTNLNNLFFHPTPKVRRQ 205
            |::||.....|||||||:|||:||||||||||.|||.|||::|.  |.:.|:| ||..:||.|||
 Frog   134 DKDLYKACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKENVLLSSDLSVLHN-FFSQSPKTRRQ 197

  Fly   206 GEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMALHDLEVQEIISIDPCHKF 270
            |||||||..|||.:||||||||||||||||||||||||||||||||:||||::.||.::||||||
 Frog   198 GEVVQKLTQMIGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDISEICTVDPCHKF 262

  Fly   271 TWCLDACIREKNVDIKRSRELQGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLIN 335
            |||||||||||.||.||:||||||||.:|:|||||||||||.||||:|||.||.|.|:.|..||:
 Frog   263 TWCLDACIREKFVDAKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLAVSTIRNLQELIS 327

  Fly   336 NEGMPRDNQILILLLRMLALGLSAWVMIDSQDFKEPKLDCQVVTKFLPALMSLMVDDQCRSLHAK 400
            .|.:|||||.|:||||||:||..||.|||||.|||||||.:::|||||.|:.|:|||...::.:|
 Frog   328 QESLPRDNQELLLLLRMLSLGHGAWDMIDSQVFKEPKLDTELITKFLPLLIGLVVDDYTYNVESK 392

  Fly   401 LPPDERESALTTIEHSGPAPDAVEAYIQESSVASILAMYYTLHTARLKDRVGVLRVLAILSACKD 465
            ||.:|:    ..:.:....||....::||:.:|..:.:|||||..:.:::..:||:|..|.....
 Frog   393 LPTEEK----VPVTYPNTLPDVFTKFLQENRIACEVGLYYTLHITKQRNKNFLLRLLPALKEMTG 453

  Fly   466 DRAYEDPFLHSLIALLIPMSEEFATEDFCTTLFDEFIFAGLTRENVTSRHMLKLLWYVHNKLPAG 530
            |.|:.|.|||...:.|..:.:||.:||||:::||.|......::....||:|:||.::|:|:...
 Frog   454 DTAFTDIFLHLFTSNLTLLGDEFGSEDFCSSVFDGFFLTSCPKKENVHRHVLRLLLHLHHKVAPA 518

  Fly   531 RLATLMKAMQPTTAHNEHIHKLYEILQERIGTGAAETPVIEAPPMEFDSPLKSVPT 586
            :|..|.||::|.....:.:.:|:..|.::| ......|..|..|...|.||.:|||
 Frog   519 KLEALQKALEPPKTSGDALKELHNTLSDKI-QQRKSPPAPEPEPPAMDLPLHAVPT 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NELF-B	NP_572402.1	COBRA1	116..588	CDD:283791	248/473 (52%)
nelfb	NP_001011448.1	COBRA1	107..575	CDD:310655	248/473 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	490	1.000	Domainoid score	I378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121600
Inparanoid	1	1.050	579	1.000	Inparanoid score	I1014
OMA	1	1.010	-	-		QHG48738
OrthoDB	1	1.010	-	-		D1095614at2759
OrthoFinder	1	1.000	-	-		FOG0008294
OrthoInspector	1	1.000	-	-		oto103762
Panther	1	1.100	-	-	LDO	PTHR13503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6276
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080