DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NELF-B and aifm3

DIOPT Version :9

Sequence 1:	NP_572402.1	Gene:	NELF-B / 31681	FlyBaseID:	FBgn0027553	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	XP_012823655.1	Gene:	aifm3 / 100493696	XenbaseID:	XB-GENE-5763104	Length:	618	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	55/257 - (21%)
Similarity:	91/257 - (35%)	Gaps:	72/257 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 TQHIDDKYLKILVRDRELYADTDTEV--KRQI----WRDNQSLFGD----EVSPLLSQYIREKEH 183
            ::.:|.:..:|.:|.:|.:...|.||  :.|:    .::...||.|    |.:.||.......:.
Frog   239 SKSMDSQAEQIFLRSKEFFHTYDIEVLTESQVVGVDTKNKMVLFKDGFRMEYNKLLIATGNTPKT 303

  Fly   184 ILFDHTNLNNLFFHPTP----KVRRQGEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCT 244
            :......|:|:|...||    ||.|...  .|.|.::|.|              ||......|..
Frog   304 LKCKGKELDNVFTIRTPEDANKVVRLAS--SKNAVIVGAS--------------FLGMEVAAYLC 352

  Fly   245 LRAELLMALHDLEVQEIISIDPCHKFTWCLDACIREK------------------NVDIKRSREL 291
            .:|      |.:.|.|:.:| |..||       :.||                  ..::...||.
Frog   353 EKA------HSVSVVELENI-PFKKF-------LGEKVGLAIMKMFENNRVKFYMQTEVSELREQ 403

  Fly   292 QGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLINNEGMPRDNQILILLLRML 353
            :|.|      :|.||....:...|...|...|:.....|    ...|:..|::..||:.:|:
Frog   404 EGKL------KEVVLKSGKVLRADVCVIGIGASPTTGFL----KQSGVALDSRGYILVNKMM 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NELF-B	NP_572402.1	COBRA1	116..588	CDD:283791	55/257 (21%)
aifm3	XP_012823655.1	Rieske_AIFL_N	70..164	CDD:239560
		Pyr_redox_2	195..493	CDD:400379	55/257 (21%)
		Reductase_C	512..>582	CDD:405449
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165164486
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930