DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hira and TAF5

DIOPT Version :9

Sequence 1:NP_572401.2 Gene:Hira / 31680 FlyBaseID:FBgn0022786 Length:1047 Species:Drosophila melanogaster
Sequence 2:NP_009757.1 Gene:TAF5 / 852497 SGDID:S000000402 Length:798 Species:Saccharomyces cerevisiae


Alignment Length:309 Identity:75/309 - (24%)
Similarity:115/309 - (37%) Gaps:79/309 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DKQIFSVDIHKDCTKFATGGQGSDCGRVVIWNLLPVLSDKAEF----------DADVPKMLCQMD 67
            :|.:..:|...||...|.|.|.|   .:.||:|     |.:..          |.|.......:.
Yeast   466 NKDMSCLDFSDDCRIAAAGFQDS---YIKIWSL-----DGSSLNNPNIALNNNDKDEDPTCKTLV 522

  Fly    68 QHLACVNCVRWSQNGQNLASGSDDKLIMIWRKSAGSSGV--------------------FGTGGM 112
            .|...|....:|.:.:.|.|||:||.:.:|.....::.|                    |.|...
Yeast   523 GHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASH 587

  Fly   113 QKNHESWKC--FYTLR---GHDGDVLDLAWSPNDVYLASCSIDNTVIIWDAQAFPHSVATLKGHT 172
            .:....|.|  .|.||   ||..||..:::.||..|:.:.|.|.|..:||... ..||....|||
Yeast   588 DQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVST-GDSVRLFLGHT 651

  Fly   173 GLVKGVSWDPLGRFLASQSDDRSIKIWN-----TMNWSLSHTITEPFEECGGTTHILRLSWSPDG 232
            ..|..::..|.||:|::.|:|..|.:|:     .:.....|          |...|..||:|.:|
Yeast   652 APVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGH----------GKNAIYSLSYSKEG 706

  Fly   233 QYLVSAHAMNGGGPTAQIIEREGW-----------KCDKDFVGHRKAVT 270
            ..|:|    .|...|.::     |           :.|:.|:|:...||
Yeast   707 NVLIS----GGADHTVRV-----WDLKKATTEPSAEPDEPFIGYLGDVT 746

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HiraNP_572401.2 WD40 <12..370 CDD:225201 75/309 (24%)
WD40 14..349 CDD:238121 75/308 (24%)
WD40 repeat 16..68 CDD:293791 13/61 (21%)
WD40 repeat 74..127 CDD:293791 16/77 (21%)
WD40 repeat 132..169 CDD:293791 11/36 (31%)
WD40 repeat 176..211 CDD:293791 9/39 (23%)
WD40 repeat 223..263 CDD:293791 11/50 (22%)
WD40 repeat 275..322 CDD:293791
WD40 repeat 328..350 CDD:293791
HIRA_B 423..442 CDD:286531
Hira 629..820 CDD:284895
TAF5NP_009757.1 LisH 55..88 CDD:128913
TFIID_NTD2 149..275 CDD:398277
WD40 458..722 CDD:238121 69/283 (24%)
WD40 repeat 470..523 CDD:293791 13/60 (22%)
WD40 repeat 529..565 CDD:293791 9/35 (26%)
WD40 repeat 570..606 CDD:293791 7/35 (20%)
WD40 repeat 613..648 CDD:293791 10/35 (29%)
WD40 repeat 654..690 CDD:293791 9/35 (26%)
WD40 repeat 697..732 CDD:293791 10/43 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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